Evidence map›Paper›PMID 39068391›Full record

Trial reportBMC oral health2024

Assessment of a combined mouthwash on pain relief in pericoronitis: a randomized clinical study.

Neman Arekhi, Nazanin Mortazavi, Emad Bahramnejad, Vahid Khouri, Mahboubeh Tajaldini, Negar Asgari, Ahmad Sohrabi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neman ArekhiDental Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Nazanin MortazaviDental Research Center, Golestan University of Medical Sciences, Gorgan, Iran. mortazavi_nazanin@yahoo.com.
Emad BahramnejadDental Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Vahid KhouriIschemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Mahboubeh TajaldiniDepartment of Animal and Poultry Physiology, Faculty of Animal Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.
Negar AsgariInfectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Ahmad SohrabiRadinmehr Veterinary Laboratory, Radin Makian Azma Mehr Ltd, Gorgan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPericoronitis, an inflammation near wisdom teeth, often occurs when they are partially emerged, especially in the lower jaw. Commonly, the gingiva partially envelops the tooth. Treatments vary from gingival surgery to extraction. This study assessed the efficacy of a mouthwash with Chlorhexidine, Benzydamine, Nanosilver, Amoxicillin, and Metronidazole for pain reduction and enhancement of maximum mouth opening in acute pericoronitis cases. MATERIALS AND

methodsIn this randomized controlled clinical trial conducted at the Gorgan Dental Faculty, 48 pericoronitis patients were randomized into two groups. The control group used a 0.12% chlorhexidine mouthwash, while the case group used a mouthwash containing Chlorhexidine, Benzydamine, Nanosilver, Amoxicillin, and Metronidazole. The study recorded Visual Analog Scale (VAS) scores for 7 days, and Maximum mouth opening (MMO) was measured at the start and after 7 days. The analysis was performed using SPSS v20.

resultsIn this study, we compared the effects of a combined mouthwash with those of a chlorhexidine mouthwash on pericoronitis in 48 patients, with an average age of 21.56 years. No significant difference in pain reduction was observed between the groups; however, both groups exhibited decreased pain and improved MMO post-treatment. The gender distribution was balanced across both groups.

conclusionThe results indicate that both chlorhexidine mouthwash and combined mouthwash significantly improved maximum mouth opening. Nonetheless, there were no notable differences in efficacy between the two groups. These findings suggest that these mouthwashes may be beneficial for oral hygiene, warranting further in-depth research.

trial registrationRegistered on 12/03/2023, registration number IRCT20230104057046N1.

Indexed as

BenzydamineChlorhexidineMouthwashesPain MeasurementPericoronitisAdolescentAdultAmoxicillinFemaleHumansMaleMetronidazolePain ManagementYoung AdultAmoxicillinBenzydamineChlorhexidineMetronidazoleMouthwashesChlorhexidineMouthwashesPainPericoronitis

Identifiers

PMID39068391
PMCPMC11283692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.