Evidence map›Paper›PMID 39068383›Full record

SynthesisBMC emergency medicine2024

Comparison of prognosis between extracorporeal CPR and conventional CPR for patients in cardiac arrest: a systematic review and meta-analysis.

Hong Zhong, Zhaohui Yin, Yanze Wang, Pei Shen, Guoli He, Shiming Huang, Jianhong Wang, Shan Huang, Li Ding, Zunwei Luo and 1 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in BMC emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hong Zhong *Emergency Department, KweiChow Moutai Hospital, Renhuai , Guizhou, 564501, China.
Zhaohui Yin *General Surgery Department, KweiChow Moutai Hospital, Renhuai , Guizhou, 564501, China.
Yanze Wang *Emergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Pei Shen *Emergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Guoli He *Emergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Shiming HuangNursing Department, Affiliated Hospital of Zunyi Medical University, Guizhou, 563003, China.
Jianhong WangEmergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Shan HuangEmergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Li DingEmergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Zunwei LuoEmergency Department, Affiliated Hospital of Zunyi Medical University, Zunyi , Guizhou, 563003, China.
Manhong ZhouEmergency Department, KweiChow Moutai Hospital, Renhuai , Guizhou, 564501, China. manahongzhou@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimCompared to the conventional cardiopulmonary resuscitation (CCPR), potential benefits of extracorporeal cardiopulmonary resuscitation (ECPR) for patients with cardiac arrest (CA) are still controversial. We aimed to determine whether ECPR can improve the prognosis of CA patients compared with CCPR.

methodsWe systematically searched PubMed, EMBASE, and Cochrane Library from database's inception to July 2023 to identify randomized controlled trials (RCTs) or cohort studies that compared ECPR with CCPR in adults (aged ≥ 16 years) with out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). This meta-analysis was performed using a random-effects model. Two researchers independently reviewed the relevance of the study, extracted data, and evaluated the quality of the included literature. The primary outcome was short-term (from hospital discharge to one month after cardiac arrest) and long-term (≥ 90 days after cardiac arrest) survival with favorable neurological status (defined as cerebral performance category scores 1 or 2). Secondary outcomes included survival at 1 months, 3-6 months, and 1 year after cardiac arrest.

resultsThe meta-analysis included 3 RCTs and 14 cohort studies involving 167,728 patients. We found that ECPR can significantly improve good neurological prognosis (RR 1.82, 95%CI 1.42-2.34, I

conclusionsThis meta-analysis indicated that ECPR had significantly better effects on good neurological prognosis and survival rate than CCPR, especially in patients with IHCA. However, more high-quality studies are needed to explore the role of ECPR in patients with OHCA.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationHeart ArrestHumansOut-of-Hospital Cardiac ArrestPrognosisCardiac arrestConventional cardiopulmonary resuscitationExtracorporeal cardiopulmonary resuscitationExtracorporeal life supportPrognosis

Identifiers

PMID39068383
PMCPMC11282673

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.