Evidence map›Paper›PMID 39068325›Full record

SynthesisAnnals of surgical oncology2025

Occurrence of Dumping Syndrome After Esophageal Cancer Surgery: Systematic Review and Meta-analysis.

Yuan Lin, Hejie Wang, Yaxin Qu, Zhiqiang Liu, Pernilla Lagergren, Shao-Hua Xie

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Health-related quality of life in esophageal cancer: a state-of-the-art review of patient-reported outcomes and an evidence and gap map.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Pooled it
  2. Symptomatic reactive hypoglycemia is highly prevalent post-esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Article
  3. Influence of dietary intake and eating patterns on reactive hypoglycemic events in patients postesophagectomy: A prospective observational study using continuous glucose monitoring.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Observational
  4. Prediction of dumping after oesophageal cancer surgery.Acta oncologica (Stockholm, Sweden) · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan Lin *School of Public Health, Fujian Medical University, Fuzhou, China.
Hejie Wang *School of Public Health, Fujian Medical University, Fuzhou, China.
Yaxin QuSchool of Public Health, Fujian Medical University, Fuzhou, China.
Zhiqiang LiuSchool of Public Health, Fujian Medical University, Fuzhou, China.
Pernilla LagergrenDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Shao-Hua XieSchool of Public Health, Fujian Medical University, Fuzhou, China. shaohua.xie@ki.se.

Funding

Fujian Medical University XRCZX2021024Swedish Cancer Society 190043Wellcome Trust 222038
6 · The paper itself

Abstract

backgroundDumping syndrome occurs frequently after esophageal cancer surgery, but the reported prevalence varied across previous studies. This systematic review and meta-analysis aimed to clarify the prevalence of dumping syndrome after esophageal cancer surgery, particularly exploring the sources of heterogeneity in previous studies.

methodsA comprehensive literature search was conducted in PubMed, MEDLINE, Web of Science, Embase, and the Cochrane Library databases, supplemented by hand-search of reference lists, through March 2023. Random-effects meta-analysis estimated the average prevalence of dumping syndrome after esophageal cancer surgery. Heterogeneity across studies was examined by the I

resultsAmong the 2949 articles retrieved from the databases, 16 articles (15 cohort studies and 1 randomized controlled trial) met the inclusion criteria. The prevalence of dumping syndrome ranged 0-74% in these studies, showing high heterogeneity (I

conclusionsOur findings revealed that dumping syndrome is common after esophageal cancer surgery. The varying prevalence across previous studies was probably owing to differences in measurement of dumping syndrome. Using specific patient reported outcome questionnaires is recommended for future investigations on dumping syndrome after esophageal cancer surgery.

Indexed as

Dumping SyndromeEsophageal NeoplasmsEsophagectomyHumansPostoperative ComplicationsPrevalencePrognosisDumping symptomsEsophageal neoplasmsEsophagectomyPostoperative complicationsSystematic review

Identifiers

PMID39068325
PMCPMC11698775

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.