Evidence map›Paper›PMID 39068250›Full record

ArticleEye (London, England)2024

An artificial intelligence platform for the screening and managing of strabismus.

Dawen Wu, Yanfei Li, Haixian Zhang, Xubo Yang, Yiji Mao, Bingjie Chen, Yi Feng, Liang Chen, Xingyu Zou, Yan Nie and 6 more

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dawen Wu *Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0002-4938-3044
Yanfei Li *Machine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Haixian ZhangMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Xubo YangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Yiji MaoMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Bingjie ChenDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Yi FengMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Liang ChenDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Xingyu ZouMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Yan NieDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Teng YinMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Zeyi YangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Jingyu LiuMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Wenyi ShangMachine Intelligence Laboratory, College of Computer Science, Sichuan University, Chengdu, China.
Guoyuan YangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China. 31981077@qq.com.
Longqian LiuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China. b.q15651@hotmail.com.ORCID http://orcid.org/0000-0002-2265-4625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesConsidering the escalating incidence of strabismus and its consequential jeopardy to binocular vision, there is an imperative demand for expeditious and precise screening methods. This study was to develop an artificial intelligence (AI) platform in the form of an applet that facilitates the screening and management of strabismus on any mobile device.

methodsThe Visual Transformer (VIT_16_224) was developed using primary gaze photos from two datasets covering different ages. The AI model was evaluated by 5-fold cross-validation set and tested on an independent test set. The diagnostic performance of the AI model was assessed by calculating the Accuracy, Precision, Specificity, Sensitivity, F1-Score and Area Under the Curve (AUC).

resultsA total of 6194 photos with corneal light-reflection (with 2938 Exotropia, 1415 Esotropia, 739 Vertical Deviation and 1562 Orthotropy) were included. In the internal validation set, the AI model achieved an Accuracy of 0.980, Precision of 0.941, Specificity of 0.979, Sensitivity of 0.958, F1-Score of 0.951 and AUC of 0.994. In the independent test set, the AI model achieved an Accuracy of 0.967, Precision of 0.980, Specificity of 0.970, Sensitivity of 0.960, F1-Score of 0.975 and AUC of 0.993.

conclusionsOur study presents an advanced AI model for strabismus screening which integrates electronic archives for comprehensive patient histories. Additionally, it includes a patient-physician interaction module for streamlined communication. This innovative platform offers a complete solution for strabismus care, from screening to long-term follow-up, advancing ophthalmology through AI technology for improved patient outcomes and eye care quality.

Indexed as

Artificial IntelligenceStrabismusAdolescentAdultChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedSensitivity and SpecificityVision, BinocularVision ScreeningYoung Adult

Identifiers

PMID39068250
PMCPMC11543679

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.