Evidence map›Paper›PMID 39068200›Full record

ArticleScientific reports2024

First voltammetric analysis of two possible anticancer drug candidates using an unmodified glassy carbon electrode.

Katarzyna Tyszczuk-Rotko, Katarzyna Staniec, Krzysztof Sztanke, Małgorzata Sztanke

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katarzyna Tyszczuk-RotkoFaculty of Chemistry, Institute of Chemical Sciences, Maria Curie-Skłodowska University in Lublin, 20-031, Lublin, Poland.
Katarzyna StaniecFaculty of Chemistry, Institute of Chemical Sciences, Maria Curie-Skłodowska University in Lublin, 20-031, Lublin, Poland.
Krzysztof SztankeLaboratory of Bioorganic Compounds Synthesis and Analysis, Medical University of Lublin, 4A Chodźki Street, 20-093, Lublin, Poland.
Małgorzata SztankeDepartment of Medical Chemistry, Medical University of Lublin, 4A Chodźki Street, 20-093, Lublin, Poland. malgorzata.sztanke@umlub.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dimethyl 2-[2-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)hydrazinylidene]butanedioate (DIHB) and 8-(3-chlorophenyl)-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione (HDIT) are promising candidates for anticancer agents, the first analytical procedures of which are presented in this paper. The commercially available unmodified glassy carbon electrode (GCE) was used as a sensor for the individual and simultaneous differential pulse voltammetric (DPV) determination of these possible anticancer drugs. The findings concerning the electrochemical behaviour indicated that DIHB and HDIT display at GCE, as a sensor, the oxidation peaks at 1.18 and 0.98 V, respectively (vs. Ag/AgCl, 3.0 mol L

Indexed as

Antineoplastic AgentsCarbonElectrochemical TechniquesElectrodesHumansLimit of DetectionOxidation-ReductionAntineoplastic AgentsCarbonDifferential pulse voltammetryGlassy carbon electrodeSpiked urine samplesTwo anticancer drug candidates

Identifiers

PMID39068200
PMCPMC11283526

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.