Evidence map›Paper›PMID 39066915›Full record

ArticleJournal of fluorescence2025

A 1,8-Naphthalimide-based Tripodal Fluorescent Chemosensor to Selectively Detect Copper Ions.

Erendra Manandhar, Blake O Day, Ke Shay M Sampson, Evelyn E Schroeder, Aimee L Ninahaza, Samantha T Aragon, Camille J Kwan, Franchesca C Tinacba, Joshua J Do, Rosanna Jees and 2 more

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Erendra ManandharDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA. emanandhar1@stmarytx.edu.
Blake O DayDepartment of Chemistry, Berea College, Berea, KY, USA.
Ke Shay M SampsonDepartment of Chemistry, Berea College, Berea, KY, USA.
Evelyn E SchroederDepartment of Chemistry, Berea College, Berea, KY, USA.
Aimee L NinahazaDepartment of Chemistry, Berea College, Berea, KY, USA.
Samantha T AragonDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA.
Camille J KwanDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA.
Franchesca C TinacbaDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA.
Joshua J DoDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA.
Rosanna JeesDepartment of Chemistry and Biochemistry, St. Mary's University, San Antonio, TX, USA.
Ram S BhattaTexas A & M University, San Antonio, TX, USA.
Peter J CraggSchool of Applied Sciences, University of Brighton, Brighton, UK.

Funding

U-RISE at St. Mary's UniversityT34GM149455 · NIGMS · ST. MARY'S UNIVERSITY · PI CONTRERAS-SHANNON, VERONICA E · 2023 to 2024
$724k
NIGMS NIH HHS T34 GM149455
6 · The paper itself

Abstract

A 1,8-naphthalimide-based tripodal fluorescent ligand (L3) was synthesized through the copper (I) catalyzed Huisgen azide-alkyne cycloaddition reaction of 2-(2-azidoethyl)-6-morpholino-1 H-benzo[de]isoquinoline-1,3(2 H)-dione with triproparagylamine. Naphthalimide acts as the fluorophore while the triazole and amine nitrogens chelate the metal ion. L3 showed a selective fluorescence turn-off for Cu(II) over other metal ions in aqueous acetonitrile solution. A Job's plot, Benesi-Hildbrand plot and high-resolution mass spectrometry data confirm a 1:1 binding stoichiometry with a binding constant of 7.8 х10

Indexed as

1,8-NaphthalimideAmineCopper ionFluorescent chemosensorTriazole

Identifiers

PMID39066915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.