Evidence map›Paper›PMID 39066605›Full record

ArticleBehavioral sleep medicine

Examining the Longitudinal Effects of Insomnia on Depression and Medication Adherence in People Living with HIV.

Juan A Esquivel-Mendoza, Satyanand Satyanarayana, Steven Safren, Brooke G Rogers

Abstract read
In one paragraph

Article in Behavioral sleep medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan A Esquivel-MendozaDepartment of Psychology, University of Miami, Miami, FL, USA.
Satyanand SatyanarayanaDepartment of Psychology, University of Miami, Miami, FL, USA.
Steven SafrenDepartment of Psychology, University of Miami, Miami, FL, USA.
Brooke G RogersDepartment of Psychiatry, Boston Medical Center, Boston, MA, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GWENDOLYN Barbara SCOTT · 2007 to 2026
$33.8M
The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Audrey Harkness · 2023 to 2026
$8.9M
Mechanisms and Health Impact of Insomnia as an HIV ComorbidityF31MH113481 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI ROGERS, BROOKE GENKIN · 2017 to 2017
$44k
NIAID NIH HHS P30 AI042853NIAID NIH HHS P30 AI073961NIMH NIH HHS F31 MH113481NIMH NIH HHS P30 MH133399
6 · The paper itself

Abstract

objectiveThe management of HIV has shifted from a focus solely on the disease to a broader perspective encompassing co-occurring medical conditions and quality of life. Mental health concerns such as depression and sleep disturbances, particularly insomnia, are often overlooked in HIV care. The aim of the study was to investigate the longitudinal impact of insomnia on depression and medication adherence among (PLWH).

methodsThis study, conducted in an urban HIV clinic, involved active patients and assessed depression, insomnia, and medication adherence at baseline, 3-month, and 6-month intervals. Hierarchical linear models were employed to analyze the fixed and random effects of time, within-person and between-person insomnia on depression, as well as the effects of time, within-person and between-person depression on ART adherence.

resultsWithin-person effects revealed that each one unit increase in the Insomnia Severity Index (ISI) was associated with a b = 0.267-point rise in Patient Health Questionnaire-9 (PHQ-9) scores (

conclusionThe study underscores the potential impact of insomnia on mental health and treatment adherence in people living with HIV (PLWH). This study emphasizes the necessity of comprehensive care models considering the interplay between sleep quality, mental health, and medication adherence for PLWH.

Indexed as

DepressionDrug MonitoringHIV InfectionsMedication AdherenceSleep Initiation and Maintenance DisordersAdultAnti-HIV AgentsFemaleHumansLongitudinal StudiesMaleMiddle AgedQuality of LifeAnti-HIV Agents

Identifiers

PMID39066605
PMCPMC11524771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.