Evidence map›Paper›PMID 39066392›Full record

ArticleVaccines2024

A Flagellin-Adjuvanted Trivalent Mucosal Vaccine Targeting Key Periodontopathic Bacteria.

Vandara Loeurng, Sao Puth, Seol Hee Hong, Yun Suhk Lee, Kamalakannan Radhakrishnan, Jeong Tae Koh, Joong-Ki Kook, Joon Haeng Rhee, Shee Eun Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vandara LoeurngClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.
Sao PuthClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.
Seol Hee HongClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.
Yun Suhk LeeClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.
Kamalakannan RadhakrishnanClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.ORCID 0000-0002-0890-8692
Jeong Tae KohDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0001-6279-6487
Joong-Ki KookKorean Collection of Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 61452, Republic of Korea.
Joon Haeng RheeClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.ORCID 0000-0003-4018-3203
Shee Eun LeeClinical Vaccine R&D Center, Chonnam National University, Hwasun-gun 58128, Republic of Korea.ORCID 0000-0002-2023-3317

Funding

Korea Health Technology R&D Project RS-2022-KH127978 (HV22C0079)National Research Foundation (NRF) of Korea 2019R1A5A2027521National Research Foundation (NRF) of Korea 2020M3A9G3080282National Research Foundation (NRF) of Korea 2020R1A5A2031185
6 · The paper itself

Abstract

Periodontal disease (PD) is caused by microbial dysbiosis and accompanying adverse inflammatory responses. Due to its high incidence and association with various systemic diseases, disease-modifying treatments that modulate dysbiosis serve as promising therapeutic approaches. In this study, to simulate the pathophysiological situation, we established a "temporary ligature plus oral infection model" that incorporates a temporary silk ligature and oral infection with a cocktail of live

Indexed as

flagellinperiodontitistrivalent mucosal vaccine

Identifiers

PMID39066392
PMCPMC11281409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.