ReviewVaccines2024
Understanding COVID-19 Vaccine Hesitancy in the United States: A Systematic Review.
Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Social media-based interventions for improving vaccine uptake, reducing hesitancy, and combating misinformation: a comprehensive systematic review and meta-analysis of RCT.BMC public health · 2026Pooled it
- Digital Intervention (MiVacunaLA 2.0) to Promote COVID-19 Vaccine Acceptance Among Hispanic Children: Community-Based Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Review
- Vaccine communication: a critical review of foundations, challenges, and future directions.NPJ vaccines · 2026Review
- Incidence of COVID-19 and Influenza-Related Outcomes and Vaccinations in the United States, October 2022 Through December 2024.Vaccines · 2026Article
- Vaccine hesitancy in the school community and among health personnel: a cross-sectional study.BMC public health · 2026Article
- Article
- The development and psychometric evaluation of vaccine hesitancy and perception scale towards COVID-19 vaccination (VHAPS-CV19).Frontiers in public health · 2026Article
- Attitudes Towards the HPV Vaccine Among Oropharyngeal Cancer Patients in a Post-COVID World.Laryngoscope investigative otolaryngology · 2025Article
- COVID- 19 vaccination reduces new-onset fibromyalgia risk in survivors.BMC medicine · 2025Article
- The role of media and community engagement in COVID-19 vaccinations in Tanzania.Journal of public health in Africa · 2025Article
- Adolescents' knowledge of and confidence in vaccines improves with board game play.Discover education · 2025Article
- Coverage with Influenza, Respiratory Syncytial Virus, and COVID-19 Vaccines Among Nursing Home Residents - National Healthcare Safety Network, United States, November 2024.MMWR. Morbidity and mortality weekly report · 2024Article
- COVID-19 Vaccine Hesitancy and Misinformation Endorsement among a Sample of Native Spanish-Speakers in the US: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Prioritization of Vaccines for Introduction in the National Immunization Program in the Republic of Korea.Vaccines · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic has presented the importance of vaccination as a pivotal strategy for controlling its spread. However, vaccine hesitancy poses a significant barrier to achieving widespread immunization in the United States. This systematic review utilizes the 5C model to examine the factors contributing to hesitancy, which include confidence in vaccines, complacency about disease risk, calculations of individual benefit, convenience of vaccination, and collective responsibility for the protection of others.
methodsWe conducted a comprehensive search across several relevant databases and the gray literature, identifying 544 studies that used quantitative and qualitative methods to explore COVID-19 vaccine hesitancy in the general U.S. POPULATION:
resultsThis review identifies a complex interplay of factors affecting hesitancy, such as concerns over vaccine safety and efficacy, misinformation and conspiracy theories, demographic variables, and socioeconomic conditions. Key strategies for increasing vaccine uptake include transparent and effective communication along with proactive community engagement.
conclusionsTo effectively mitigate vaccine hesitancy, it is crucial to understand its multifaceted causes. Tailored interventions that consider socioeconomic and cultural contexts and prioritize clear communication, community involvement, and specific strategies to address unique concerns can enhance vaccine acceptance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.