Evidence map›Paper›PMID 39066343›Full record

ArticleVaccines2024

Feline Infectious Peritonitis mRNA Vaccine Elicits Both Humoral and Cellular Immune Responses in Mice.

Terza Brostoff, Hannah P Savage, Kenneth A Jackson, Joseph C Dutra, Justin H Fontaine, Dennis J Hartigan-O'Connor, Randy P Carney, Patricia A Pesavento

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Terza BrostoffDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-4825-4881
Hannah P SavageDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-1057-7239
Kenneth A JacksonDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Joseph C DutraDepartment of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-5553-5200
Justin H FontaineDepartment of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA.
Dennis J Hartigan-O'ConnorDepartment of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA.
Randy P CarneyDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616, USA.ORCID 0000-0001-8193-1664
Patricia A PesaventoDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0001-6593-9607

Funding

Morris Animal Foundation D23FE-302SOCK-FIP fund at the Center for Companion Animal Health - UC Davis 2022-62-F
6 · The paper itself

Abstract

Feline infectious peritonitis (FIP) is a devastating and often fatal disease caused by feline coronavirus (FCoV). Currently, there is no widely used vaccine for FIP, and many attempts using a variety of platforms have been largely unsuccessful due to the disease's highly complicated pathogenesis. One such complication is antibody-dependent enhancement (ADE) seen in FIP, which occurs when sub-neutralizing antibody responses to viral

Indexed as

feline coronavirusfeline infectious peritonitismRNA vaccinenucleocapsid

Identifiers

PMID39066343
PMCPMC11281389

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.