Evidence map›Paper›PMID 39066321›Full record

ArticleViruses2024

Detection of Enteric Viruses in Children under Five Years of Age before and after Rotavirus Vaccine Introduction in Manhiça District, Southern Mozambique, 2008-2019.

Percina Chirinda, Filomena Manjate, Marcelino Garrine, Augusto Messa, Nélio Nobela, Delfino Vubil, Tacilta Nhampossa, Sozinho Acácio, Quique Bassat, Karen L Kotloff and 8 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Percina ChirindaCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0002-2649-1034
Filomena ManjateCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0003-3632-2047
Marcelino GarrineCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0002-8619-8761
Augusto MessaCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0002-1794-2462
Nélio NobelaCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
Delfino VubilCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0001-9139-5594
Tacilta NhampossaCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
Sozinho AcácioCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
Quique BassatCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0003-0875-7596
Karen L KotloffCenter for Vaccine Development, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Myron M LevineCenter for Vaccine Development, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0002-5721-5040
James P NataroDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Jacqueline E TateCenters for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
Umesh ParasharCenters for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
Jason M MwendaWorld Health Organization (WHO), Regional Office for Africa, Brazzaville P.O. Box 2465, Congo.
Pedro L AlonsoCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
Eva D JoãoCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
Inácio MandomandoCentro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.ORCID 0000-0002-1078-2187

Funding

Centers for Disease Control and Prevention (CDC), Atlanta, and the World Health Organization, Regional Office for Africa (WHO/AFRO) MOA #..870-15 SCFundo Nacional de Investigação (FNI), Moçambique 245-INVGates Foundation OPP1033572United States Agency for International Development AID-656-F-16-00002World Health Organization 001
6 · The paper itself

Abstract

Enteric viruses are the leading cause of diarrhoea in children <5 years. Despite existing studies describing rotavirus diarrhoea in Mozambique, data on other enteric viruses remains scarce, especially after rotavirus vaccine introduction. We explored the prevalence of norovirus GI and GII, adenovirus 40/41, astrovirus, and sapovirus in children <5 years with moderate-to-severe (MSD), less severe (LSD) diarrhoea and community healthy controls, before (2008-2012) and after (2016-2019) rotavirus vaccine introduction in Manhiça District, Mozambique. The viruses were detected using ELISA and conventional reverse transcription PCR from stool samples. Overall, all of the viruses except norovirus GI were significantly more detected after rotavirus vaccine introduction compared to the period before vaccine introduction: norovirus GII in MSD (13/195, 6.7% vs. 24/886, 2.7%, respectively;

Indexed as

DiarrheaFecesRotavirus VaccinesChild, PreschoolFemaleGastroenteritisHumansInfantInfant, NewbornMaleMozambiqueNorovirusPrevalenceRotavirusRotavirus InfectionsSapovirusRotavirus Vaccineschildrendiarrhoeaenteric virusesMozambiquerotavirus vaccine

Identifiers

PMID39066321
PMCPMC11281453

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.