Evidence map›Paper›PMID 39066245›Full record

ArticleViruses2024

Reversibility of Neuropsychiatric Adverse Events after Switching to Darunavir/Cobicistat or Doravirine in Men on INSTI-Based Regimen.

José Antonio Mata-Marín, Carina Aurora Juárez-Contreras, Mara Soraya Rodríguez-Evaristo, Olivia Concepción Martínez-Carrizales, Ericka Pompa-Mera, Alberto Chaparro Sánchez, Salma Triana-González, Ana Luz Cano-Díaz, Jesús Enrique Gaytán-Martínez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

José Antonio Mata-MarínInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Carina Aurora Juárez-ContrerasInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Mara Soraya Rodríguez-EvaristoInternal Medicine Department, Hospital de Especialidades, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.ORCID 0000-0002-8566-4003
Olivia Concepción Martínez-CarrizalesPsychiatric Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Ericka Pompa-MeraResearch Unit, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Alberto Chaparro SánchezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Salma Triana-GonzálezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.
Ana Luz Cano-DíazInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.ORCID 0000-0001-9659-746X
Jesús Enrique Gaytán-MartínezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrase strand transfer inhibitors (INSTI) are associated with neuropsychiatric adverse events (NPAEs). The aim of this study was to evaluate improvements in NPAEs after switching an INSTI-based regimen to darunavir/cobicistat (DRV/c) or doravirine (DOR).

Indexed as

CobicistatDarunavirHIV InfectionsPyridonesAdultAnti-HIV AgentsDrug SubstitutionHeterocyclic Compounds, 3-RingHIV Integrase InhibitorsHumansMaleMiddle AgedPiperazinesProspective StudiesSleep Initiation and Maintenance DisordersTriazolesAnti-HIV AgentsCobicistatDarunavirdoravirineHeterocyclic Compounds, 3-RingHIV Integrase InhibitorsPiperazinesPyridonesTriazolesdarunavirdoravirineinsomniaintegraseneuropsychiatric

Identifiers

PMID39066245
PMCPMC11281698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.