Evidence map›Paper›PMID 39066223›Full record

ReviewViruses2024

Exploring the Complexities of Long COVID.

Jackson Donald, Shymaa E Bilasy, Catherine Yang, Ahmed El-Shamy

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Evolutionary Predictors of Post-COVID Syndrome.Journal of clinical medicine · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Impact of Physical Activity on Long COVID Symptoms Among College Students: A Retrospective Study.International journal of environmental research and public health · 2025
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jackson DonaldCollege of Graduate Studies, California Northstate University, 9700 West Taron Drive, Elk Grove, CA 95757, USA.
Shymaa E BilasyCollege of Dental Medicine, California Northstate University, 9700 West Taron Drive, Elk Grove, CA 95757, USA.ORCID 0000-0002-4967-583X
Catherine YangCollege of Graduate Studies, California Northstate University, 9700 West Taron Drive, Elk Grove, CA 95757, USA.
Ahmed El-ShamyCollege of Graduate Studies, California Northstate University, 9700 West Taron Drive, Elk Grove, CA 95757, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the emergence of the SARS-CoV-2 virus in 2019, nearly 700 million COVID-19 cases and 7 million deaths have been reported globally. Despite most individuals recovering within four weeks, the Center for Disease Control (CDC) estimates that 7.5% to 41% develop post-acute infection syndrome (PAIS), known as 'Long COVID'. This review provides current statistics on Long COVID's prevalence, explores hypotheses concerning epidemiological factors, such as age, gender, comorbidities, initial COVID-19 severity, and vaccine interactions, and delves into potential mechanisms, including immune responses, viral persistence, and gut dysbiosis. Moreover, we conclude that women, advanced age, comorbidities, non-vaccination, and low socioeconomic status all appear to be risk factors. The reasons for these differences are still not fully understood and likely involve a complex relationship between social, genetic, hormonal, and other factors. Furthermore, individuals with Long COVID-19 seem more likely to endure economic hardship due to persistent symptoms. In summary, our findings further illustrate the multifaceted nature of Long COVID and underscore the importance of understanding the epidemiological factors and potential mechanisms needed to develop effective therapeutic strategies and interventions.

Indexed as

COVID-19Post-Acute COVID-19 SyndromeSARS-CoV-2ComorbidityDysbiosisFemaleHumansMalePrevalenceRisk FactorsLong COVIDpost COVID-19 conditionSARS-CoV-2

Identifiers

PMID39066223
PMCPMC11281588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.