Evidence map›Paper›PMID 39066207›Full record

ArticleViruses2024

Safety and DIVA Capability of Novel Live Attenuated Classical Swine Fever Marker Vaccine Candidates in Pregnant Sows.

Chao Tong, Alice Mundt, Alexandra Meindl-Boehmer, Verena Haist, Andreas Gallei, Ning Chen

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao TongBoehringer Ingelheim Vetmedica (China) Co., Ltd., No. 299, Xiangtai Road, Taizhou 225300, China.
Alice MundtBoehringer Ingelheim Vetmedica GmbH, Binger Str. 173, 55216 Ingelheim am Rhein, Germany.
Alexandra Meindl-BoehmerBoehringer Ingelheim Vetmedica GmbH, Binger Str. 173, 55216 Ingelheim am Rhein, Germany.
Verena HaistBoehringer Ingelheim Vetmedica GmbH, Binger Str. 173, 55216 Ingelheim am Rhein, Germany.
Andreas GalleiBoehringer Ingelheim Vetmedica GmbH, Binger Str. 173, 55216 Ingelheim am Rhein, Germany.
Ning ChenBoehringer Ingelheim Vetmedica (China) Co., Ltd., No. 299, Xiangtai Road, Taizhou 225300, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical Swine Fever (CSF), a highly contagious viral disease affecting pigs and wild boar, results in significant economic losses in the swine industry. In endemic regions, prophylactic vaccination and stamping-out strategies are used to control CSF outbreaks. However, sporadic outbreaks and persistent infections continue to be reported. Although the conventional attenuated CSF vaccines protect pigs against the disease, they do not allow for the differentiation of infected from vaccinated animals (DIVA), limiting their use as an eradication tool. In this study, three targeted attenuation strategies were employed to generate vaccine candidates based on the current prevalent CSFV group 2 strains GD18 and QZ07: a single deletion of H79 in E

Indexed as

Antibodies, ViralClassical Swine FeverClassical Swine Fever VirusVaccines, AttenuatedViral VaccinesAnimalsAntibodies, NeutralizingFemalePregnancySwineVaccinationVaccines, MarkerAntibodies, NeutralizingAntibodies, ViralVaccines, AttenuatedVaccines, MarkerViral Vaccinesclassical swine feverDIVA vaccinepregnant sowsafetyvertical transmission

Identifiers

PMID39066207
PMCPMC11281586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.