Evidence map›Paper›PMID 39065808›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Unlocking the Green Gold: Exploring the Cancer Treatment and the Other Therapeutic Potential of Fucoxanthin Derivatives from Microalgae.

Fatouma Mohamed Abdoul-Latif, Ayoub Ainane, Ibrahim Houmed Aboubaker, Ali Merito Ali, Houda Mohamed, Pannaga Pavan Jutur, Tarik Ainane

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatouma Mohamed Abdoul-LatifCenter for Research and Study of Djibouti, Medicinal Research Institute, Djibouti City P.O. Box 486, Djibouti.ORCID 0000-0001-7213-4700
Ayoub AinaneSuperior School of Technology, University of Sultan Moulay Slimane, P.O. Box 170, Khenifra 54000, Morocco.ORCID 0000-0002-5004-6416
Ibrahim Houmed AboubakerCenter for Research and Study of Djibouti, Medicinal Research Institute, Djibouti City P.O. Box 486, Djibouti.
Ali Merito AliCenter for Research and Study of Djibouti, Medicinal Research Institute, Djibouti City P.O. Box 486, Djibouti.
Houda MohamedCenter for Research and Study of Djibouti, Medicinal Research Institute, Djibouti City P.O. Box 486, Djibouti.
Pannaga Pavan JuturOmics of Algae Group, Industrial Biotechnology, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.ORCID 0000-0001-7988-2883
Tarik AinaneSuperior School of Technology, University of Sultan Moulay Slimane, P.O. Box 170, Khenifra 54000, Morocco.ORCID 0000-0001-6743-2666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fucoxanthin, a carotenoid widely studied in marine microalgae, is at the heart of scientific research because of its promising bioactive properties for human health. Its unique chemical structure and specific biosynthesis, characterized by complex enzymatic conversion in marine organisms, have been examined in depth in this review. The antioxidant, anti-inflammatory, and anti-cancer activities of fucoxanthin have been rigorously supported by data from in vitro and in vivo experiments and early clinical trials. Additionally, this review explores emerging strategies to optimize the stability and efficacy of fucoxanthin, aiming to increase its solubility and bioavailability to enhance its therapeutic applications. However, despite these potential benefits, challenges persist, such as limited bioavailability and technological obstacles hindering its large-scale production. The medical exploitation of fucoxanthin thus requires an innovative approach and continuous optimization to overcome these barriers. Although further research is needed to refine its clinical use, fucoxanthin offers promising potential in the development of natural therapies aimed at improving human health. By integrating knowledge about its biosynthesis, mechanisms of action, and potential beneficial effects, future studies could open new perspectives in the treatment of cancer and other chronic diseases.

Indexed as

anti-cancerbiochemistryfucoxanthinmicroalgaeprospectstherapeutic

Identifiers

PMID39065808
PMCPMC11280058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.