Evidence map›Paper›PMID 39065740›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

2D/3D-QSAR Model Development Based on a Quinoline Pharmacophoric Core for the Inhibition of

Marcos Lorca, Gisela C Muscia, Susana Pérez-Benavente, José M Bautista, Alison Acosta, Cesar González, Gianfranco Sabadini, Jaime Mella, Silvia E Asís, Marco Mellado

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Design of Hybrid Quinoline-Chalcone Compounds AgainstPharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcos LorcaInstituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2360102, Chile.
Gisela C MusciaDepartamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, C1113AAB Ciudad Autónoma de Buenos Aires, Buenos Aires 1113, Argentina.
Susana Pérez-BenaventeDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.
José M BautistaDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-8926-881X
Alison AcostaUniversidad Andres Bello, Facultad de Ciencias Exactas, Departamento de Ciencias Químicas, Viña del Mar 2531015, Chile.
Cesar GonzálezDepartamento de Química, Universidad Técnica Federico Santa María, Av. España 1680, Valparaíso 2390123, Chile.ORCID 0000-0002-0830-8507
Gianfranco SabadiniInstituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2360102, Chile.ORCID 0009-0009-1925-3167
Jaime MellaInstituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2360102, Chile.ORCID 0000-0002-2434-8461
Silvia E AsísDepartamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, C1113AAB Ciudad Autónoma de Buenos Aires, Buenos Aires 1113, Argentina.ORCID 0000-0002-3978-8638
Marco MelladoFacultad de Medicina y Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile.ORCID 0000-0001-9577-5180

Funding

Agencia Nacional de Investigación y Desarrollo Beca ANID 21230194Agencia Nacional de Investigación y Desarrollo Beca ANID-PFCHA/Doctorado Nacional/2018-21180427Agencia Nacional de Investigación y Desarrollo Beca Doctorado Nacional ANID N°21210742Agencia Nacional de Investigación y Desarrollo FONDECYT grant number 1240289Agencia Nacional de Investigación y Desarrollo Subvencion en la Academia SA77210078University of Valparaíso PROYECTO PUENTE UVA 22991
6 · The paper itself

Abstract

Malaria is an infectious disease caused by

Indexed as

2D- and 3D-QSAR modelsbiocompatibilitydrug designexperimental validationmalariaquinoline synthesis

Identifiers

PMID39065740
PMCPMC11279914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.