Evidence map›Paper›PMID 39065683›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Targeted Delivery Strategies for Multiple Myeloma and Their Adverse Drug Reactions.

Shuting Li, Hongjie Wang, Shijun Xiong, Jing Liu, Shuming Sun

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuting LiXiangya School of Medicine, Central South University, Changsha 410011, China.
Hongjie WangXiangya School of Medicine, Central South University, Changsha 410011, China.
Shijun XiongXiangya School of Medicine, Central South University, Changsha 410011, China.
Jing LiuXiangya School of Medicine, Central South University, Changsha 410011, China.ORCID 0000-0001-5588-3865
Shuming SunXiangya School of Medicine, Central South University, Changsha 410011, China.ORCID 0000-0001-7525-8979

Funding

Provincial Natural Science Foundation of Hunan 2022JJ30784the National Natural Science Foundation of China 81770107the National Natural Science Foundation of China 81920108004
6 · The paper itself

Abstract

Currently, multiple myeloma (MM) is a prevalent hematopoietic system malignancy, known for its insidious onset and unfavorable prognosis. Recently developed chemotherapy drugs for MM have exhibited promising therapeutic outcomes. Nevertheless, to overcome the shortcomings of traditional clinical drug treatment, such as off-target effects, multiple drug resistance, and systemic toxicity, targeted drug delivery systems are optimizing the conventional pharmaceuticals for precise delivery to designated sites at controlled rates, striving for maximal efficacy and safety, presenting a promising approach for MM treatment. This review will delve into the outstanding performance of antibody-drug conjugates, peptide-drug conjugates, aptamer-drug conjugates, and nanocarrier drug delivery systems in preclinical studies or clinical trials for MM and monitor their adverse reactions during treatment.

Indexed as

drug delivery systemmultiple myelomatargeted therapy

Identifiers

PMID39065683
PMCPMC11279695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.