Evidence map›Paper›PMID 39065658›Full record

ArticlePharmaceutics2024

Upgrading Mitochondria-Targeting Peptide-Based Nanocomplexes for Zebrafish In Vivo Compatibility Assays.

Rúben Faria, Eric Vivès, Prisca Boisguérin, Simon Descamps, Ângela Sousa, Diana Costa

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Self-Assembling Short Peptide Carriers for Gene Delivery.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rúben FariaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0002-4500-0018
Eric VivèsPhyMedExp, University of Montpellier, INSERM, CNRS, 34295 Montpellier, France.ORCID 0000-0001-5391-9641
Prisca BoisguérinPhyMedExp, University of Montpellier, INSERM, CNRS, 34295 Montpellier, France.ORCID 0000-0002-6955-1340
Simon DescampsCRBM-CNRS, Cell Biology Research of Montpellier, UMR5237, 34293 Montpellier, France.
Ângela SousaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0001-9155-7581
Diana CostaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0002-5049-4518

Funding

Fundação para a Ciência e Tecnologia CICS-UBI projects UIDB/00709/2020 and UIDP/00709/2020Fundação para a Ciência e Tecnologia DCosta:2021.03946.CEECIND Researcher Contract and R. Faria: PhD Grant SFRH/BD/148393/2019.
6 · The paper itself

Abstract

The lack of effective delivery systems has slowed the development of mitochondrial gene therapy. Delivery systems based on cell-penetrating peptides (CPPs) like the WRAP (tryptophan and arginine-rich peptide) family conjugated with a mitochondrial targeting sequence (MTS) have emerged as adequate carriers to mediate gene expression into the mitochondria. In this work, we performed the PEGylation of WRAP/pDNA nanocomplexes and compared them with previously analyzed nanocomplexes such as (KH)

Indexed as

cell-penetrating peptideshemocompatibilityin vivo toxicitymitochondria-targetingpeptide-based nanoparticlesZebrafish embryo model

Identifiers

PMID39065658
PMCPMC11281276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.