Evidence map›Paper›PMID 39065630›Full record

ArticlePharmaceutics2024

Evaluating and Managing the Microbial Contamination of Eye Drops: A Two-Phase Hospital-Based Study.

Léa Roquefeuil, Katia Iskandar, Christine Roques, Loïc Marchin, Mylène Guittard, Hélène Poupet, Marie-Laure Brandely-Piat, Marion Jobard

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Léa RoquefeuilUnité de Préparations Stériles Ophtalmologiques et Oncologiques, GHU AP-HP Centre-Université de Paris Cité-Site Cochin, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France.
Katia IskandarDepartment of Pharmacy, School of Pharmacy, Lebanese International University, Beirut 1105, Lebanon.ORCID 0000-0001-5544-6681
Christine RoquesLaboratoire de Génie Chimique, CNRS, INPT, UPS, Faculté de Pharmacie, Université de Toulouse, 31062 Toulouse, France.
Loïc MarchinPylote SAS, 22 Avenue de la Mouyssaguèse, 31280 Drémil-Lafage, France.
Mylène GuittardPylote SAS, 22 Avenue de la Mouyssaguèse, 31280 Drémil-Lafage, France.
Hélène PoupetLaboratoire de Bactériologie, GHU AP-HP Centre-Université de Paris Cité-Site Cochin, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France.
Marie-Laure Brandely-PiatUnité de Préparations Stériles Ophtalmologiques et Oncologiques, GHU AP-HP Centre-Université de Paris Cité-Site Cochin, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France.
Marion JobardUnité de Préparations Stériles Ophtalmologiques et Oncologiques, GHU AP-HP Centre-Université de Paris Cité-Site Cochin, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbial contamination of eye drop tips and caps varies between 7.7% and 100%. In seeking patient protection and continuous improvement, the Pharmacy Department in the Sterile Ophthalmological and Oncological Preparations Unit at Cochin Hospital AP-HP, Paris, France, conducted a two-phase study to compare the antimicrobial efficiency and practical use of standard packaging and a marketed eye drop container incorporating a self-decontaminating antimicrobial green technology by Pylote SAS at the tip and cap sites. The first phase was conducted in situ to identify the microbial contaminants of eye drops used in the hospital and community settings. A total of 110 eye drops were included for testing.

Indexed as

antimicrobial surfacecapceramicdropper tipeye dropsmicrobial contaminationmineral oxide

Identifiers

PMID39065630
PMCPMC11279954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.