Evidence map›Paper›PMID 39064983›Full record

ArticleMolecules (Basel, Switzerland)2024

Deposition of Human-Serum-Albumin-Functionalized Spheroidal Particles on Abiotic Surfaces: Reference Kinetic Results for Bioparticles.

Małgorzata Nattich-Rak, Marta Sadowska, Zbigniew Adamczyk, Teresa Basinska, Damian Mickiewicz, Mariusz Gadzinowski

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Małgorzata Nattich-RakJerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Niezapominajek 8, 30-239 Cracow, Poland.ORCID 0000-0002-5025-8611
Marta SadowskaJerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Niezapominajek 8, 30-239 Cracow, Poland.ORCID 0000-0001-5482-5989
Zbigniew AdamczykJerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Niezapominajek 8, 30-239 Cracow, Poland.ORCID 0000-0002-8358-3656
Teresa BasinskaCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Henryka Sienkiewicza 112, 90-363 Lodz, Poland.
Damian MickiewiczCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Henryka Sienkiewicza 112, 90-363 Lodz, Poland.
Mariusz GadzinowskiCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Henryka Sienkiewicza 112, 90-363 Lodz, Poland.ORCID 0000-0001-6266-6199

Funding

This work was supported by the Statutory activity of the Jerzy Haber Institute of Catalysis and Surface Chemistry PAS and by the Research Project of the National Science Center (Poland). Grant. (synthesis of the spheroidal particles) UMO-2018/29/BST8/ 01721
6 · The paper itself

Abstract

Human serum albumin (HSA) corona formation on polymer microparticles of a spheroidal shape was studied using dynamic light scattering and Laser Doppler Velocimetry (LDV). Physicochemical characteristics of the albumin comprising the zeta potential and the isoelectric point were determined as a function of pH for various ionic strengths. Analogous characteristics of the polymer particles were analyzed. The adsorption of albumin on the particles was in situ monitored by LDV. The stability of the HSA-functionalized particle suspensions under various pHs and their electrokinetic properties were also determined. The deposition kinetics of the particles on mica, silica and gold sensors were investigated by optical microscopy, AFM and quartz microbalance (QCM) under diffusion and flow conditions. The obtained results were interpreted in terms of the random sequential adsorption model that allowed to estimate the range of applicability of QCM for determining the deposition kinetics of viruses and bacteria at abiotic surfaces.

Indexed as

Serum Albumin, HumanAdsorptionGoldHumansHydrogen-Ion ConcentrationKineticsOsmolar ConcentrationParticle SizeQuartz Crystal Microbalance TechniquesSilicon DioxideSurface PropertiesGoldSerum Albumin, HumanSilicon Dioxidealbumin coronas on particlesbacteria depositiondeposition of albumin polymer particle conjugatesHSA-functionalized particlesquartz microbalance measurementsspheroidal polymer particleszeta potential of albumin corona

Identifiers

PMID39064983
PMCPMC11279952

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.