Evidence map›Paper›PMID 39064904›Full record

ArticleMolecules (Basel, Switzerland)2024

Self-Assembly of Rhein and Matrine Nanoparticles for Enhanced Wound Healing.

Xunxun Wu, Ranqing Zang, Yiting Qiu, Ni Yang, Meiyan Liu, Site Wei, Xianxiang Xu, Yong Diao

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xunxun WuSchool of Medicine, Huaqiao University, Quanzhou 362021, China.ORCID 0000-0003-1536-634X
Ranqing ZangSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Yiting QiuSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Ni YangSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Meiyan LiuSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Site WeiSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Xianxiang XuSchool of Medicine, Huaqiao University, Quanzhou 362021, China.
Yong DiaoSchool of Medicine, Huaqiao University, Quanzhou 362021, China.ORCID 0000-0002-0633-1906

Funding

National Natural Science Foundation of China 82304762Natural Science Foundation of Fujian Province 2022J05062Natural Science Foundation of Xiamen 3502Z20227041the Scientific Research Funds of Huaqiao University 21BS126
6 · The paper itself

Abstract

Carrier-free self-assembly has gradually shifted the focus of research on natural products, which effectively improve the bioavailability and the drug-loading rate. However, in spite of the existing studies, the development of self-assembled natural phytochemicals that possess pharmacological effects still has scope for further exploration and enhancement. Herein, a nano-delivery system was fabricated through the direct self-assembly of Rhein and Matrine and was identified as a self-assembled Rhein-Matrine nanoparticles (RM NPs). The morphology of RM NPs was characterized by TEM. The molecular mechanisms of self-assembly were explored using FT-IR,

Indexed as

AlkaloidsAnthraquinonesMatrinesMolecular Dynamics SimulationNanoparticlesQuinolizinesWound HealingAnimalsDrug CarriersHumansHydrogelsMiceAlkaloidsAnthraquinonesDrug CarriersHydrogelsMatrinesQuinolizinesrheinhydrogelMatrinenanoparticleRheinself-assemblywound healing

Identifiers

PMID39064904
PMCPMC11279319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.