Evidence map›Paper›PMID 39064870›Full record

ReviewMolecules (Basel, Switzerland)2024

Principal Bioactive Properties of Oleanolic Acid, Its Derivatives, and Analogues.

Fatin Jannus, Juan Sainz, Fernando J Reyes-Zurita

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  7. Influence of Ultrasound-Assisted and Supercritical COMolecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatin JannusDepartment of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Av. Fuentenueva, 18071 Granada, Spain.ORCID 0000-0001-7419-8492
Juan SainzDepartment of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Av. Fuentenueva, 18071 Granada, Spain.ORCID 0000-0002-9355-2423
Fernando J Reyes-ZuritaDepartment of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Av. Fuentenueva, 18071 Granada, Spain.ORCID 0000-0003-3438-0753

Funding

Instituto de Salud Carlos III PI17/02256Regional Government of Andalusia B-FQM-650-UGR-20
6 · The paper itself

Abstract

Natural products have always played an important role in pharmacotherapy, helping to control pathophysiological processes associated with human disease. Thus, natural products such as oleanolic acid (OA), a pentacyclic triterpene that has demonstrated important activities in several disease models, are in high demand. The relevant properties of this compound have motivated re-searchers to search for new analogues and derivatives using the OA as a scaffold to which new functional groups have been added or modifications have been realized. OA and its derivatives have been shown to be effective in the treatment of inflammatory processes, triggered by chronic diseases or bacterial and viral infections. OA and its derivatives have also been found to be effective in diabetic disorders, a group of common endocrine diseases characterized by hyperglycemia that can affect several organs, including the liver and brain. This group of compounds has been reported to exhibit significant bioactivity against cancer processes in vitro and in vivo. In this review, we summarize the bioactive properties of OA and its derivatives as anti-inflammatory, anti-bacterial, antiviral, anti-diabetic, hepatoprotective, neuroprotective, and anticancer agents.

Indexed as

Oleanolic AcidAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntiviral AgentsHumansHypoglycemic AgentsNeuroprotective AgentsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntiviral AgentsHypoglycemic AgentsNeuroprotective AgentsOleanolic Acidantibacterialanticancerantidiabeticanti-inflammatoryantiviralhepatoprotectiveneuro-protectiveoleanolic acid

Identifiers

PMID39064870
PMCPMC11279785

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.