Observational studyNutrients2024
The Impact of Malnutrition on Chronic Obstructive Pulmonary Disease (COPD) Outcomes: The Predictive Value of the Mini Nutritional Assessment (MNA) versus Acute Exacerbations in Patients with Highly Complex COPD and Its Clinical and Prognostic Implications.
Observational study in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The interrelationship between nutritional risk, psychological factors, and quality of life in chronic obstructive pulmonary disease (COPD): a hospital-based cross-sectional study.Irish journal of medical science · 2026Article
- Diagnostic value of geriatric nutritional risk index and phase angle for malnutrition in patients with COPD: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Impact of Nutritional Status and Sarcopenia on Acute Exacerbation Risk in Stable Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
- VE-VCO2 Slope During Cardiopulmonary Exercise Test Predicts Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Association between controlling nutritional status (CONUT) and all-cause mortality in elderly hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Clinical characteristics and outcomes of chronic obstructive pulmonary disease patients with family history of chronic airway disease.Annals of medicine · 2025Article
- Comparison of the predictive performance of Cumulative Illness Rating Scale, Charlson Comorbidity Index and COMCOLD Index for moderate-to-severe exacerbations in elderly subjects with chronic obstructive pulmonary disease.Annals of medicine · 2025Observational
- Prediction of 12-month exacerbation-related readmission in hospitalized patients with COPD: a single-center study in China.European journal of medical research · 2025Article
- Exploring the link: nutritional status and chronic obstructive pulmonary disease - insights from NHANES and clinical research.BMC pulmonary medicine · 2025Article
- Association between CRP-Albumin-Lymphocyte (CALLY) index and Asthma-COPD overlap: analysis of NHANES 2015-2018 data.BMC pulmonary medicine · 2025Article
- Predictive Value of Geriatric Nutritional Risk Index for Readmission within 6-Months in Elderly Inpatients with Acute Exacerbation Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025Article
- Association between nutritional risk and clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease.American journal of translational research · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent management of COPD is predominantly focused on respiratory aspects. A multidimensional assessment including nutritional assessment, quality of life and disability provides a more reliable perspective of the true complexity of COPD patients.
methodsThis was a prospective observational study of 120 elderly COPD patients at high risk of acute exacerbations. The Mini Nutritional Assessment (MNA) was administered in addition to the usual respiratory assessment. The primary outcome was a composite of moderate or severe acute exacerbations during 52 weeks of follow-up.
resultsThe median MNA Short Form (SF) score was 11 (8-12), 39 participants (32.50%) had a normal nutritional status, 57 (47.5%) were at risk of malnutrition and 24 (20%) were malnourished. Our multivariate linear regression models showed that the MNA score was associated with dyspnea and respiratory symptom severity, assessed by the Modified British Medical Research Council (mMRC) scale and the COPD Assessment Test (CAT) score, with spirometric variables, in particular with the severity of airflow limitation based on the value of FEV1, and with poorer QoL, as assessed by the EQ-5D-3 questionnaire. Competing risk analysis according to nutritional status based on the MNA Total Score showed that COPD participants "at risk of malnutrition" and "malnourished" had a higher risk of moderate to severe acute exacerbations with sub-hazard ratios of 3.08 (1.40-6.80),
conclusionOur study confirms the importance of assessing nutritional status in elderly COPD patients and its prognostic value.
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