Evidence map›Paper›PMID 39064727›Full record

Trial reportNutrients2024

Comparative Effects of

Cindy Bandala, Jazmín Carro-Rodríguez, Noemí Cárdenas-Rodríguez, Itzel Peña-Montero, Modesto Gómez-López, Ana Paola Hernández-Roldán, Juan Carlos Huerta-Cruz, Felipe Muñoz-González, Iván Ignacio-Mejía, Brayan Domínguez and 1 more

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cindy BandalaLaboratorio de Neurociencia Traslacional Aplicada a Enfermedades Crónicas y Emergentes, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Jazmín Carro-RodríguezLaboratorio de Neurociencia Traslacional Aplicada a Enfermedades Crónicas y Emergentes, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-3862-4762
Noemí Cárdenas-RodríguezLaboratorio de Neurociencias, Instituto Nacional de Pediatría, Mexico City 04530, Mexico.ORCID 0000-0002-6580-3440
Itzel Peña-MonteroLaboratorio de Obesidad, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Modesto Gómez-LópezLaboratorio de Obesidad, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Ana Paola Hernández-RoldánLaboratorio de Neurociencia Traslacional Aplicada a Enfermedades Crónicas y Emergentes, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Juan Carlos Huerta-CruzUnidad de Investigación en Farmacología, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosio Villegas, Secretaria de Salud, Mexico City 14080, Mexico.
Felipe Muñoz-GonzálezLaboratorio de Neurociencia Traslacional Aplicada a Enfermedades Crónicas y Emergentes, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-4221-9479
Iván Ignacio-MejíaLaboratorio de Medicina Traslacional, Escuela Militar de Graduados en Sanidad, Universidad del Ejército y Fuerza Aérea, Mexico City 11200, Mexico.ORCID 0000-0003-3792-4613
Brayan DomínguezLaboratorio de Neurociencia Traslacional Aplicada a Enfermedades Crónicas y Emergentes, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Eleazar Lara-PadillaLaboratorio de Obesidad, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.

Funding

Instituto Politécnico Nacional 2170253Wellcome Trust 221826
6 · The paper itself

Abstract

METHODOLOGY: We performed a comparative study in 50 adult Mexican patients with obesity treated with GS or BBR for 3 months. The baseline and final biochemical parameters, body composition, blood pressure, gene expression of Res, Ome, Vis, and Ap, and safety parameters were evaluated.

resultsBBR significantly decreased (

conclusionIn patients with obesity, BBR has a better effect on body composition, blood pressure, and the gene expression of adipokines related to metabolic risk, while GS has a better effect on fasting glucose and adipokines related to insulin resistance, with minimal side effects.

Indexed as

AdipokinesBerberineBody CompositionGymnema sylvestreObesityResistinAdultAnti-Obesity AgentsApelinBlood GlucoseBlood PressureCytokinesFemaleGPI-Linked ProteinsHumansLectinsAdipokinesAnti-Obesity AgentsApelinBerberineBlood GlucoseCytokinesGPI-Linked ProteinsITLN1 protein, humanLectinsNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanPlant ExtractsResistinRETN protein, humanadipokineapelinberberinebody compositionfasting glucosegene expressionGymnema sylvestreobesityomentinresistinvisfatin

Identifiers

PMID39064727
PMCPMC11280467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.