Evidence map›Paper›PMID 39064681›Full record

Trial reportNutrients2024

A Novel Nutraceutical Supplement Lowers Postprandial Glucose and Insulin Levels upon a Carbohydrate-Rich Meal or Sucrose Drink Intake in Healthy Individuals-A Randomized, Placebo-Controlled, Crossover Feeding Study.

Giriprasad Venugopal, Rishikesh Dash, Siwani Agrawal, Sayantan Ray, Prasanta Kumar Sahoo, Balamurugan Ramadass

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giriprasad VenugopalCenter of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar 751019, India.ORCID 0000-0002-4982-9237
Rishikesh DashCenter of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar 751019, India.ORCID 0009-0009-8705-9323
Siwani AgrawalDepartment of Biochemistry, All India Institute of Medical Sciences, Bhubaneswar 751019, India.ORCID 0009-0005-1387-7711
Sayantan RayDepartment of Endocrinology, All India Institute of Medical Sciences, Bhubaneswar 751019, India.
Prasanta Kumar SahooDepartment of Ayurveda (AYUSH), All India Institute of Medical Sciences, Bhubaneswar 751019, India.ORCID 0000-0003-0348-4293
Balamurugan RamadassCenter of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar 751019, India.ORCID 0000-0002-8158-230X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlkaloid- and polyphenol-rich white mulberry leaf and apple peel extracts have been shown to have potential glucose-lowering effects, benefitting the control of postprandial blood glucose levels. This study aimed to determine the effect of the combination of

methodsThis study was designed as a randomized, crossover, single-blinded clinical trial. Out of 116 healthy participants, 85 subjects (aged 18-60 years) completed the day 1 and 5 crossover study. On day 1, subjects were supplemented with a placebo or GLUBLOC

resultsSignificant changes in total iAUC (0-120 min), Cmax, and Tmax of postprandial blood glucose and insulin levels were noticed upon GLUBLOC

conclusionsPremeal supplementation with GLUBLOC

Indexed as

Blood GlucoseCross-Over StudiesDietary CarbohydratesDietary SupplementsInsulinMorusPlant ExtractsPostprandial PeriodAdolescentAdultBeveragesFemaleHealthy VolunteersHumansMaleMalusBlood GlucoseDietary CarbohydratesInsulinPlant ExtractsSucrosecarbohydrate-rich mealGLUBLOCTMglucose loweringglucose tolerancehyperglycemiasucrose drink

Identifiers

PMID39064681
PMCPMC11280099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.