Evidence map›Paper›PMID 39064648›Full record

Trial reportNutrients2024

Impact of Combined Prebiotic Galacto-Oligosaccharides and

Beyda Beteri, Monica Barone, Silvia Turroni, Patrizia Brigidi, George Tzortzis, Jelena Vulevic, Karol Sekulic, Diana-Elena Motei, Adele Costabile

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Probiotics,Metabolism open · 2025
    Article
  18. Dietary fibre and the gut microbiome: implications for glucose homeostasis.Current opinion in clinical nutrition and metabolic care · 2025
    Review
  19. Postbiotics: an insightful review of the latest category in functional biotics.World journal of microbiology & biotechnology · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beyda BeteriSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0009-0001-4293-6697
Monica BaroneHuman Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-5229-570X
Silvia TurroniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-2345-9482
Patrizia BrigidiHuman Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
George TzortzisveMico Ltd., Amelia House, Crescent Road, Worthing BN11 1RL, UK.
Jelena VulevicveMico Ltd., Amelia House, Crescent Road, Worthing BN11 1RL, UK.ORCID 0000-0003-2274-3537
Karol SekulicAlberta Health Services, Edmonton, AB T5J 3E4, Canada.
Diana-Elena MoteiSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.
Adele CostabileSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0000-0003-3185-030X

Funding

veMico Ltd. Ref. LSC/2021/43
6 · The paper itself

Abstract

The complex interactions between intestinal microbiota and metabolic disorders are well-documented, with implications for glucose metabolism, energy expenditure, and intestinal permeability. Prebiotics induce beneficial changes in gut microbiota composition in prediabetes, while postbiotics can enhance gut barrier function, complementing each other to improve glucose metabolism and insulin sensitivity. This study investigated the effects of a 12-week dietary fibre (DF) supplement on gut health, metabolic function, and diet. The supplement contained konjac glucomannan (KGM), galacto-oligosaccharides (GOSs), and exopolysaccharides (EPSs) from

Indexed as

Bifidobacterium breveDietary FiberGastrointestinal MicrobiomeGlycated HemoglobinMannansOligosaccharidesPrebioticsPrediabetic StateAdultBlood GlucoseDietary SupplementsDouble-Blind MethodFemaleGalactoseHumansMale(1-6)-alpha-glucomannanBlood GlucoseDietary FiberGalactoseGlycated Hemoglobinhemoglobin A1c protein, humanMannansOligosaccharidesPrebioticsBifidobacterium brevegut microbiomepostbioticsprediabetes

Identifiers

PMID39064648
PMCPMC11280236

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.