Evidence map›Paper›PMID 39064639›Full record

Trial reportNutrients2024

Effects of Nasal Solution Incorporating Resveratrol and Carboxymethyl-Β-Glucan in Preschool Non-Atopic Children with Wheezing.

Cristiana Indolfi, Costanza Mignini, Francesco Valitutti, Ilaria Bizzarri, Giulio Dinardo, Angela Klain, Michele Miraglia Del Giudice, Giuseppe Di Cara

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristiana IndolfiDepartment of Woman, Child and of General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Costanza MigniniDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.
Francesco ValituttiDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.ORCID 0000-0002-1473-2240
Ilaria BizzarriDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.
Giulio DinardoDepartment of Woman, Child and of General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-9952-1206
Angela KlainDepartment of Woman, Child and of General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0001-7823-2125
Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-8369-5957
Giuseppe Di CaraDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.ORCID 0000-0002-7632-6774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper respiratory tract infections (URTI) account for more than 80% of wheezing episodes in children with a high incidence of hospitalization in preschool age. Most children with symptoms of wheezing during an URTI are usually non-atopic. As the majority of wheezing episodes resulting from URTI are attributed to viral triggers, several studies have suggested the potential anti-inflammatory and antiviral properties of resveratrol. This study aims to identify the effect of resveratrol for pediatric non-atopic patients with recurrent wheezing triggered by URTIs. We conducted a prospective single-blind study to assess the effectiveness of a short course of nasal solutions incorporating resveratrol and carboxymethyl-β-glucan, administered for 7 days at the onset of URTIs, compared to standard nasal lavage with 0.9% saline solution. A total of 19 patients entered the active group, 20 patients were assigned to the placebo group. The comparison of overall wheezing days (

Indexed as

beta-GlucansRespiratory SoundsRespiratory Tract InfectionsResveratrolAdministration, IntranasalChild, PreschoolFemaleHumansMaleNasal LavageProspective StudiesSingle-Blind MethodTreatment Outcomebeta-Glucanscarboxymethyl-beta-1,3-glucanResveratrolchildrennon-atopic childrennutraceuticalnutraceuticspediatric populationspreschool wheezingrespiratory infectionsrespiratory tract diseasesresveratrolwheezing

Identifiers

PMID39064639
PMCPMC11280398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.