Evidence map›Paper›PMID 39064589›Full record

ArticleMedicina (Kaunas, Lithuania)2024

Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27

Antonio Cigliano, Maria M Simile, Gianpaolo Vidili, Giovanni M Pes, Maria P Dore, Francesco Urigo, Eleonora Cossu, Li Che, Claudio Feo, Sara M Steinmann and 5 more

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Antonio CiglianoDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Maria M SimileDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Gianpaolo VidiliDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-8903-5829
Giovanni M PesDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0003-3265-2823
Maria P DoreDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7305-3531
Francesco UrigoDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0009-0004-8273-5509
Eleonora CossuInstitute of Pathology, University of Regensburg, 93053 Regensburg, Germany.
Li CheDepartment of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Fracisco, CA 94143, USA.
Claudio FeoDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-4475-3405
Sara M SteinmannInstitute of Pathology, University of Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-9284-1138
Silvia RibbackInstitute of Pathology, University of Greifswald, 17489 Greifswald, Germany.
Rosa M PascaleDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7612-3646
Matthias EvertInstitute of Pathology, University of Regensburg, 93053 Regensburg, Germany.
Xin ChenDepartment of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Fracisco, CA 94143, USA.
Diego F CalvisiDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
Signaling pathways during hepatocarcinogenesisR01CA239251 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI CHEN, XIN · 2020 to 2024
$1.8M
Italian Association Cancer Research IG19175NIDDK NIH HHS P30 DK026743NIH grant R01CA239251UCSF Liver Center P30DK026743
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, HepatocellularCyclin-Dependent Kinase Inhibitor p27Liver NeoplasmsS-Phase Kinase-Associated ProteinsAnimalsCell Line, TumorDown-RegulationFatty Acid SynthasesFatty Acid Synthase, Type IHumansMaleMiceCyclin-Dependent Kinase Inhibitor p27FASN protein, humanFatty Acid SynthasesFatty Acid Synthase, Type ISKP2 protein, humanS-Phase Kinase-Associated ProteinsFASNhepatocellular carcinomalipogenesismouse modelsp27KIP1SKP2

Identifiers

PMID39064589
PMCPMC11278665

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.