ArticleMicromachines2024
An Optofluidic Young Interferometer for Electrokinetic Transport-Coupled Biosensing.
Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Evanescent wave-based optical biosensors for innovations, medical application and future perspectives.Journal of advanced research · 2026Review
- Review of Recent Optofluidic Devices.Micromachines · 2026Article
- Surface Relief Gratings of Slide-Ring Hydrogels for Label-Free Biosensing.Gels (Basel, Switzerland) · 2025Article
- Resonant Young's Slit Interferometer for Sensitive Detection of Low-Molecular-Weight Biomarkers.Biosensors · 2025Article
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Authors and funding
2 authors.
Funding
Abstract
Label-free optical biosensors, such as interferometers, can provide a comparable limit of detection to widely used enzyme-linked immunosorbent assays while minimizing the number of steps and reducing false positives/negatives. In 2020, the authors reported on a novel optofluidic Young interferometer (YI) that could provide real-time spatial information on refractive index changes occurring along the length of the sensor and reference channels. Herein, we exploit these features of the YI to study interactions of biomolecules with recognition elements immobilized in selected regions of agarose gel in the sensor channel. We show that the YI is well suited for the biosensing of an exemplar biomolecule, streptavidin, in the absence and presence of the bovine serum albumin interferent. Equally, we couple the YI with electrokinetic transport to reduce the time needed for biosensing.
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Registered trials
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