Evidence map›Paper›PMID 39064329›Full record

ArticleMicromachines2024

Label-Free Continuous Cell Sorting Using Optofluidic Chip.

Yingjie Zhang, Tao Zhang, Xinchun Zhang, Jingmeng Cheng, Sixiang Zhang

Abstract read
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingjie ZhangDepartment of Mechanical Engineering, North China Electric Power University, Baoding 071003, China.ORCID 0009-0007-5059-2058
Tao ZhangDepartment of Mechanical Engineering, North China Electric Power University, Baoding 071003, China.
Xinchun ZhangDepartment of Mechanical Engineering, North China Electric Power University, Baoding 071003, China.ORCID 0000-0001-7978-9435
Jingmeng ChengSchool of Mechanical Engineering, Hebei University of Technology, Tianjin 300000, China.
Sixiang ZhangSchool of Mechanical Engineering, Hebei University of Technology, Tianjin 300000, China.

Funding

Basic Research Priorities Program of Baoding of Hebei Province of China 2372P018Natural Science Foundation of Hebei Province of China A2020502005 ; A2021201010
6 · The paper itself

Abstract

In the field of biomedicine, efficiently and non-invasively isolating target cells has always been one of the core challenges. Optical fiber tweezers offer precise and non-invasive manipulation of cells within a medium and can be easily integrated with microfluidic systems. Therefore, this paper investigated the mechanism of cell manipulation using scattering force with optical fiber tweezers. We employed flat-ended single-mode fiber to drive and sort cells and derived the corresponding scattering force formula based on the T-matrix model. A single-mode optical tweezers system for cell sorting was developed, and an optofluidic experimental platform was constructed that effectively integrates the optical system with microfluidic chips. The chip, featuring an expanded cross-channel design, successfully achieved continuous separation of yeast cells (8~10 µm in diameter) and polystyrene microspheres (15~20 µm in diameter), with a sorting efficiency of up to 86% and maintaining viability in approximately 90% of the yeast cells. Compared to other sorting systems, this system does not require labeling and can achieve continuous sorting with cell viability at a lower cost of instrumentation.

Indexed as

cell sortingchiphigh viabilitylabel-freeoptofluidicsscattering forceT-matrix

Identifiers

PMID39064329
PMCPMC11278515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.