ReviewJournal of clinical medicine2024
Clinical and Experimental Evidence for Patient Self-Inflicted Lung Injury (P-SILI) and Bedside Monitoring.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Volatile anesthetic sedation in acute respiratory distress syndrome.Intensive care medicine · 2026Review
- ARDS 60th anniversary: spontaneous breathing in ARDS.Intensive care medicine · 2026Article
- The Geometry of Circulatory Shock: A Conceptual Multi-Scale Lagrangian Framework for Physiology-Informed Hemodynamic Phenotyping.Journal of clinical medicine · 2026Review
- Non-Invasive Respiratory Support in "De Novo" Acute Hypoxemic Respiratory Failure: Which Technique Is Best?Medicina (Kaunas, Lithuania) · 2026Review
- Beyond One-Size-Fits-All: Precision Mechanical Ventilation in ARDS.Journal of clinical medicine · 2026Review
- [Correlation of occlusion pressure with sedation in non-neurocritical patients].Revista medica del Instituto Mexicano del Seguro Social · 2026Observational
- Patient Self-Inflicted Lung Injury in ARDS: From Physiological Concept to Clinical Syndrome.Journal of clinical medicine · 2026Review
- Atelectrauma: promotion and prevention.Intensive care medicine · 2026Article
- Respiratory pyramid interface (RPI): a conceptual three-dimensional pyramid model for visualization of lung mechanics during mechanical ventilation.Frontiers in physiology · 2026Article
- When mechanical power remains high despite conventional lung-protective settings: a physiology-driven bedside framework.Annals of intensive care · 2026Review
- Physiology-guided personalized mechanical ventilation to prevent ventilator-induced lung injury.Frontiers in medicine · 2026Review
- Decoding lung-kidney interactions in sepsis: an integrated view of molecular mechanisms, pathophysiology, and therapeutic interventions.Frontiers in immunology · 2026Review
- Monitoring of invasive assisted mechanical ventilation: a good clinical practice document by the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI).Journal of anesthesia, analgesia and critical care · 2025Review
- Association between controlled mechanical ventilation and systemic inflammation in acute hypoxemic respiratory failure: an observational cohort study.Critical care (London, England) · 2025Observational
- Omics approach to chest electrical impedance tomography reveals physiological cluster of ARDS characterised by increased respiratory drive and effort.Annals of intensive care · 2025Article
- Case Report: Spontaneous Pneumomediastinum and Pneumothorax Complicating Severe Ketoacidosis-An Unexpected Presentation.Reports (MDPI) · 2025Article
- Patient-Self Inflicted Lung Injury (P-SILI): An Insight into the Pathophysiology of Lung Injury and Management.Journal of clinical medicine · 2025Review
- Are we prepared to monitor and prevent patient self-inflicted lung injury (P-SILI) during mechanical ventilation in pediatric patients?Einstein (Sao Paulo, Brazil) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patient self-inflicted lung injury (P-SILI) is a major challenge for the ICU physician: although spontaneous breathing is associated with physiological benefits, in patients with acute respiratory distress syndrome (ARDS), the risk of uncontrolled inspiratory effort leading to additional injury needs to be assessed to avoid delayed intubation and increased mortality. In the present review, we analyze the available clinical and experimental evidence supporting the existence of lung injury caused by uncontrolled high inspiratory effort, we discuss the pathophysiological mechanisms by which increased effort causes P-SILI, and, finally, we consider the measurements and interpretation of bedside physiological measures of increased drive that should alert the clinician. The data presented in this review could help to recognize injurious respiratory patterns that may trigger P-SILI and to prevent it.
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Registered trials
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