Evidence map›Paper›PMID 39064016›Full record

ArticleJournal of personalized medicine2024

Diagnostic Performance of Point-of-Care High-Sensitivity Troponin in the Exclusion of Non-ST-Elevation Myocardial Infarction in the Emergency Department.

Daniel Zalama-Sánchez, Carlos Del Pozo Vegas, Ancor Sanz-García, Pedro Ángel de Santos-Castro, Javier Presencio-Dominguez, Pablo González-Izquierdo, Susana Sánchez-Ramón, Leyre Teresa Pinilla-Arribas, Manuel Baladrón-Segura, Jaldún Cheayeb-Morán and 4 more

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. How Close Are We to Patient-Side Troponin Testing?Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel Zalama-SánchezEmergency Department, Hospital Universitario Virgen de la Victoria, 29010 Málaga, Spain.
Carlos Del Pozo VegasFaculty of Medicine, University of Valladolid, 47002 Valladolid, Spain.ORCID 0000-0001-5561-1384
Ancor Sanz-GarcíaFaculty of Health Sciences, University of Castilla la Mancha, 45600 Talavera de la Reina, Spain.ORCID 0000-0002-5024-5108
Pedro Ángel de Santos-CastroEmergency Department, Hospital Clínico Universitario, 47003 Valladolid, Spain.
Javier Presencio-DominguezEmergency Department, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.
Pablo González-IzquierdoEmergency Department, Hospital Clínico Universitario, 47003 Valladolid, Spain.
Susana Sánchez-RamónEmergency Department, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.
Leyre Teresa Pinilla-ArribasEmergency Department, Hospital Clínico Universitario, 47003 Valladolid, Spain.
Manuel Baladrón-SeguraClinical Analysis Department, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.ORCID 0009-0007-7669-9507
Jaldún Cheayeb-MoránEmergency Department, Hospital Clínico Universitario, 47003 Valladolid, Spain.
María Fernandez-GarcíaClinical Analysis Department, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.
Guillermo Velasco de CosClinical Analysis Department, Hospital Clínico Universitario, 47003 Valladolid, Spain.ORCID 0000-0002-7260-3789
Raúl López-IzquierdoFaculty of Medicine, University of Valladolid, 47002 Valladolid, Spain.ORCID 0000-0001-5092-4138
Francisco Martín-RodríguezFaculty of Medicine, University of Valladolid, 47002 Valladolid, Spain.

Funding

BIOTEC MEDICA NA
6 · The paper itself

Abstract

backgroundThis study evaluates the diagnostic performance of high-sensitivity troponin using point-of-care testing (POCT) devices compared with main laboratory measurements for ruling out non-ST-elevation myocardial infarction (NSTEMI) in emergency department (ED) patients presenting with non-traumatic chest pain.

methodsThis multicenter, observational, prospective, non-interventional study was conducted in two Spanish hospitals from 1 June to 31 December 2023 and included adult patients presenting with non-traumatic chest pain admitted to the ED. High-sensitivity troponin levels were measured using both the Siemens Atellica

resultsOf the 201 patients who met the inclusion criteria, a significant correlation was observed between the POCT and laboratory assays. The area under the curve (AUC) of the ROC curve was consistently greater than 0.9, indicating a high diagnostic accuracy for ruling out NSTEMI. In addition, measurement times were significantly reduced using POCT compared to the core laboratory.

conclusionThese results suggest that high-sensitivity troponin POCT devices offer comparable diagnostic performance to traditional laboratory methods for the diagnosis of NSTEMI in the emergency department, potentially speeding up clinical decisions and optimizing resource utilization.

Indexed as

emergency departmentnon-ST-elevation myocardial infarctionpoint-of-care testingtroponin

Identifiers

PMID39064016
PMCPMC11277698

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.