Evidence map›Paper›PMID 39063961›Full record

ArticleJournal of personalized medicine2024

The Relative Apical Sparing Strain Pattern in Severe Aortic Valve Stenosis: A Marker of Adverse Cardiac Remodeling.

Dovilė Ramanauskaitė, Giedrė Balčiūnaitė, Darius Palionis, Justinas Besusparis, Edvardas Žurauskas, Vilius Janušauskas, Aleksejus Zorinas, Nomeda Valevičienė, Peter Sogaard, Sigita Glaveckaitė

Abstract read
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In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dovilė RamanauskaitėClinic of Cardiovascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.ORCID 0009-0003-2865-1673
Giedrė BalčiūnaitėClinic of Cardiovascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.ORCID 0000-0001-7447-3001
Darius PalionisDepartment of Radiology, Nuclear Medicine and Medical Physics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.
Justinas BesusparisDepartment of Pathology, Forensic Medicine and Pharmacology, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, P. Baublio Str. 5, LT-08406 Vilnius, Lithuania.
Edvardas ŽurauskasDepartment of Pathology, Forensic Medicine and Pharmacology, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, P. Baublio Str. 5, LT-08406 Vilnius, Lithuania.
Vilius JanušauskasClinic of Cardiovascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.ORCID 0000-0001-8492-8428
Aleksejus ZorinasClinic of Cardiovascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.ORCID 0000-0003-4283-492X
Nomeda ValevičienėDepartment of Radiology, Nuclear Medicine and Medical Physics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.
Peter SogaardDepartament of Cardiology, Faculty of Medicine, Department of Clinical Medicine, Aalborg University Hospital, Hobrovej 18-22, 9100 Aalborg, Denmark.
Sigita GlaveckaitėClinic of Cardiovascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Santariškių Str. 2, LT-08410 Vilnius, Lithuania.ORCID 0000-0002-5291-9954

Funding

Lietuvos Mokslo Taryba 09.3.3-LMT-K-712
6 · The paper itself

Abstract

backgroundThe presence of a relative apical sparing (RAS) echocardiographic strain pattern raises a suspicion of underlying cardiac amyloidosis (CA). However, it is also increasingly observed in patients with aortic stenosis (AS). We aimed to evaluate the prevalence, dynamics, and clinical characteristics of the RAS strain pattern in severe AS patients who had been referred for surgical aortic valve replacement (SAVR).

methodsA total of 77 patients with severe AS and without CA were included with a mean age of 70 (62-73) years, 58% female, a mean aortic valve area index of 0.45 ± 0.1 cm

resultsAn RAS strain pattern was detected in 14 (18%) patients. RAS-positive patients had a significantly higher LV mass index (125 ± 28 g/m

conclusionsOur findings suggest that the RAS strain pattern can be present in patients with severe AS without evidence of CA. The presence of an RAS strain pattern is associated with adverse LV remodeling, and it resolves after SAVR.

Indexed as

aortic stenosisaortic valve replacementcardiac amyloidosisrelative apical sparingspeckle-tracking echocardiography

Identifiers

PMID39063961
PMCPMC11277935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.