Evidence map›Paper›PMID 39063578›Full record

ArticleLife (Basel, Switzerland)2024

A Probiotic Amylase Blend Positively Impacts Gut Microbiota Modulation in a Randomized, Placebo-Controlled, Double-Blind Study.

Mahmoud A Ghannoum, Mohammed Elshaer, Hilmi Al-Shakhshir, Mauricio Retuerto, Thomas S McCormick

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahmoud A GhannoumDepartment of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Mohammed ElshaerDepartment of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Hilmi Al-ShakhshirDepartment of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Mauricio RetuertoDepartment of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Thomas S McCormickDepartment of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.

Funding

The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI AMITABH CHAK · 2015 to 2026
$15.6M
Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infectionR01AI172944 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Mahmoud A Ghannoum, Thomas S Mccormick · 2023 to 2026
$2.5M
BIOHM Health, LLC, BH10072.NIAID NIH HHS R01 AI172944NIDDK NIH HHS P30 DK097948
6 · The paper itself

Abstract

The present study was performed to determine if ingesting a blend of probiotics plus amylase would alter the abundance and diversity of gut microbiota in subjects consuming the blend over a 6-week period. 16S and ITS ribosomal RNA (rRNA) sequencing was performed on fecal samples provided by subjects who participated in a clinical study where they consumed either a probiotic amylase blend (

Indexed as

bacteriaCandidafungigut healthmicroorganisms

Identifiers

PMID39063578
PMCPMC11277872

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.