Evidence map›Paper›PMID 39063444›Full record

ArticleInternational journal of environmental research and public health2024

Random Forest and Feature Importance Measures for Discriminating the Most Influential Environmental Factors in Predicting Cardiovascular and Respiratory Diseases.

Francesco Cappelli, Gianfranco Castronuovo, Salvatore Grimaldi, Vito Telesca

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  5. Review
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  8. Article
  9. Machine Learning-Based Random Forest to Predict 3-Year Survival after Endovascular Aneurysm Repair.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francesco CappelliDIBAF Department, University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-6173-5583
Gianfranco CastronuovoSchool of Engineering, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Salvatore GrimaldiDIBAF Department, University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0001-5715-106X
Vito TelescaSchool of Engineering, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0003-3235-8712

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies suggest that environmental and climatic factors are linked to the risk of mortality due to cardiovascular and respiratory diseases; however, it is still unclear which are the most influential ones. This study sheds light on the potentiality of a data-driven statistical approach by providing a case study analysis.

methodsDaily admissions to the emergency room for cardiovascular and respiratory diseases are jointly analyzed with daily environmental and climatic parameter values (temperature, atmospheric pressure, relative humidity, carbon monoxide, ozone, particulate matter, and nitrogen dioxide). The Random Forest (RF) model and feature importance measure (FMI) techniques (permutation feature importance (PFI), Shapley Additive exPlanations (SHAP) feature importance, and the derivative-based importance measure (κALE)) are applied for discriminating the role of each environmental and climatic parameter. Data are pre-processed to remove trend and seasonal behavior using the Seasonal Trend Decomposition (STL) method and preliminary analyzed to avoid redundancy of information.

resultsThe RF performance is encouraging, being able to predict cardiovascular and respiratory disease admissions with a mean absolute relative error of 0.04 and 0.05 cases per day, respectively. Feature importance measures discriminate parameter behaviors providing importance rankings. Indeed, only three parameters (temperature, atmospheric pressure, and carbon monoxide) were responsible for most of the total prediction accuracy.

conclusionsData-driven and statistical tools, like the feature importance measure, are promising for discriminating the role of environmental and climatic factors in predicting the risk related to cardiovascular and respiratory diseases. Our results reveal the potential of employing these tools in public health policy applications for the development of early warning systems that address health risks associated with climate change, and improving disease prevention strategies.

Indexed as

Cardiovascular DiseasesRespiratory Tract DiseasesAir PollutantsCarbon MonoxideEmergency Service, HospitalHumansModels, StatisticalRandom ForestAir PollutantsCarbon MonoxideCardiovascular DiseasesFeature Importance MeasuresInterpretabilityMachine LearningPublic HealthRespiratory Diseases

Identifiers

PMID39063444
PMCPMC11276884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.