Evidence map›Paper›PMID 39063243›Full record

ArticleInternational journal of molecular sciences2024

A Systematic Hierarchical Virtual Screening Model for RhlR Inhibitors Based on PCA, Pharmacophore, Docking, and Molecular Dynamics.

Jiarui Du, Jiahao Li, Juqi Wen, Jun Liu, Haichuan Xiao, Antian Zhang, Dongdong Yang, Pinghua Sun, Haibo Zhou, Jun Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Mutant-Selective Binding ofInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiarui DuCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Jiahao LiCollege of Pharmacy, Jinan University, Guangzhou 511436, China.ORCID 0000-0003-4734-5383
Juqi WenCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Jun LiuCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Haichuan XiaoCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Antian ZhangCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Dongdong YangCollege of Pharmacy, Jinan University, Guangzhou 511436, China.ORCID 0009-0000-5028-5305
Pinghua SunCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Haibo ZhouCollege of Pharmacy, Jinan University, Guangzhou 511436, China.
Jun XuCollege of Pharmacy, Jinan University, Guangzhou 511436, China.ORCID 0000-0001-6056-7381

Funding

by Natural Science Foundation of Guangdong Province 2022A1515010300China Postdoctoral Science Foundation no. 55350658
6 · The paper itself

Abstract

RhlR plays a key role in the quorum sensing of

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationPrincipal Component AnalysisPseudomonas aeruginosaAnti-Bacterial AgentsBacterial ProteinsDrug Evaluation, PreclinicalLigandsPharmacophoreProtein BindingQuorum SensingStructure-Activity RelationshipAnti-Bacterial AgentsBacterial ProteinsLigandsmolecular dockingmolecular dynamicspharmacophore modelingquorum sensingRhlRSARvirtual screening

Identifiers

PMID39063243
PMCPMC11276863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.