Evidence map›Paper›PMID 39063188›Full record

ArticleInternational journal of molecular sciences2024

An Adaptable Protocol to Generate a Murine Enteroid-Macrophage Co-Culture System.

Viktoria Hentschel, Deepalakshmi Govindarajan, Thomas Seufferlein, Milena Armacki

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Viktoria HentschelDepartment of Internal Medicine 1, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.ORCID 0000-0001-8117-3023
Deepalakshmi GovindarajanDepartment of Internal Medicine 1, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Thomas SeufferleinDepartment of Internal Medicine 1, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Milena ArmackiDepartment of Internal Medicine 1, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.

Funding

Deutsche Forschungsgemeinschaft No. 1: AR 1123/3-1 - AO 676868, No. 2: 251293561
6 · The paper itself

Abstract

Impairment of the intestinal epithelial barrier is frequently seen as collateral damage in various local and systemic inflammatory conditions. The inflammatory process is characterized by reciprocal interactions between the host intestinal epithelium and mucosal innate immune cells, e.g., macrophages. This article provides step-by-step instructions on how to set up a murine enteroid-macrophage co-culture by culturing cellular elements in proximity separated by a porous membrane. Unlike previously published co-culture systems, we have combined enteroids grown from

Indexed as

Coculture TechniquesMacrophagesMice, Inbred C57BLAnimalsCell DifferentiationCells, CulturedCulture Media, ConditionedIntestinal MucosaMiceOrganoidsCulture Media, Conditionedco-cultureintestinal organoidsmacrophages

Identifiers

PMID39063188
PMCPMC11277128

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.