Evidence map›Paper›PMID 39063081›Full record

ReviewInternational journal of molecular sciences2024

Hydrogels Based on Proteins Cross-Linked with Carbonyl Derivatives of Polysaccharides, with Biomedical Applications.

Chahrazed Mahmoudi, Naïma Tahraoui Douma, Hacene Mahmoudi, Camelia Elena Iurciuc Tincu, Marcel Popa

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  15. Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chahrazed MahmoudiLaboratory of Water and Environment, Faculty of Technology, University Hassiba Benbouali of Chlef, Chlef 02000, Algeria.
Naïma Tahraoui DoumaLaboratory of Water and Environment, Faculty of Technology, University Hassiba Benbouali of Chlef, Chlef 02000, Algeria.
Hacene MahmoudiNational Higher School of Nanosciences and Nanotechnologies, Algiers 16000, Algeria.
Camelia Elena Iurciuc TincuDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Protection of the Environment, "Gheorghe Asachi" Technical University, 700050 Iasi, Romania.
Marcel PopaDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Protection of the Environment, "Gheorghe Asachi" Technical University, 700050 Iasi, Romania.ORCID 0000-0003-4929-0830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adding carbonyl groups into the hydrogel matrix improves the stability and biocompatibility of the hydrogels, making them suitable for different biomedical applications. In this review article, we will discuss the use of hydrogels based on polysaccharides modified by oxidation, with particular attention paid to the introduction of carbonyl groups. These hydrogels have been developed for several applications in tissue engineering, drug delivery, and wound healing. The review article discusses the mechanism by which oxidized polysaccharides can introduce carbonyl groups, leading to the development of hydrogels through cross-linking with proteins. These hydrogels have tunable mechanical properties and improved biocompatibility. Hydrogels have dynamic properties that make them promising biomaterials for various biomedical applications. This paper comprehensively analyzes hydrogels based on cross-linked proteins with carbonyl groups derived from oxidized polysaccharides, including microparticles, nanoparticles, and films. The applications of these hydrogels in tissue engineering, drug delivery, and wound healing are also discussed.

Indexed as

Biocompatible MaterialsDrug Delivery SystemsHydrogelsPolysaccharidesProteinsTissue EngineeringWound HealingAnimalsCross-Linking ReagentsHumansOxidation-ReductionBiocompatible MaterialsCross-Linking ReagentsHydrogelsPolysaccharidesProteinsbiomedical applicationscarbonyl groupshydrogelspolysaccharidesSchiff base

Identifiers

PMID39063081
PMCPMC11277554

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.