Evidence map›Paper›PMID 39063030›Full record

ReviewInternational journal of molecular sciences2024

Guardians under Siege: Exploring Pollution's Effects on Human Immunity.

Gaspare Drago, Noemi Aloi, Silvia Ruggieri, Alessandra Longo, Maria Lia Contrino, Fabio Massimo Contarino, Fabio Cibella, Paolo Colombo, Valeria Longo

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The toxic footprint of lead exposure: oxido-inflammatory biomarkers in urban populations of Niger Delta, Nigeria.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gaspare DragoInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0001-8475-1001
Noemi AloiInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0002-6424-8588
Silvia RuggieriInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0002-7657-6490
Alessandra LongoInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.
Maria Lia ContrinoAzienda Sanitaria Provinciale di Siracusa, Corso Gelone 17, 96100 Siracusa, Italy.
Fabio Massimo ContarinoAzienda Sanitaria Provinciale di Siracusa, Corso Gelone 17, 96100 Siracusa, Italy.
Fabio CibellaInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0003-1674-2263
Paolo ColomboInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0002-0908-1359
Valeria LongoInstitute for Biomedical Research and Innovation, National Research Council of Italy (IRIB-CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.

Funding

Italian Ministry of Health Progetto Obiettivo Piano Sanitario Nazionale 2019 - Linea 4 - Piano Nazionale Prevenzione della Regione Siciliana
6 · The paper itself

Abstract

Chemical pollution poses a significant threat to human health, with detrimental effects on various physiological systems, including the respiratory, cardiovascular, mental, and perinatal domains. While the impact of pollution on these systems has been extensively studied, the intricate relationship between chemical pollution and immunity remains a critical area of investigation. The focus of this study is to elucidate the relationship between chemical pollution and human immunity. To accomplish this task, this study presents a comprehensive review that encompasses in vitro, ex vivo, and in vivo studies, shedding light on the ways in which chemical pollution can modulate human immunity. Our aim is to unveil the complex mechanisms by which environmental contaminants compromise the delicate balance of the body's defense systems going beyond the well-established associations with defense systems and delving into the less-explored link between chemical exposure and various immune disorders, adding urgency to our understanding of the underlying mechanisms and their implications for public health.

Indexed as

Environmental PollutionAnimalsEnvironmental ExposureEnvironmental PollutantsHumansImmune SystemImmunityEnvironmental Pollutantsdevelopmental toxicologyenvironmental pollutantimmunomodulationinnate and adaptive immunitypregnancy

Identifiers

PMID39063030
PMCPMC11277414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.