Evidence map›Paper›PMID 39062979›Full record

ReviewInternational journal of molecular sciences2024

Autotaxin-Lysophosphatidate Axis: Promoter of Cancer Development and Possible Therapeutic Implications.

Carmelo Laface, Angela Dalia Ricci, Simona Vallarelli, Carmela Ostuni, Alessandro Rizzo, Francesca Ambrogio, Matteo Centonze, Annalisa Schirizzi, Giampiero De Leonardis, Rosalba D'Alessandro and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carmelo LafaceMedical Oncology Unit, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Angela Dalia RicciMedical Oncology Unit, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Simona VallarelliMedical Oncology Unit, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Carmela OstuniMedical Oncology Unit, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Alessandro RizzoMedical Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", Viale Orazio Flacco 65, 70124 Bari, Italy.ORCID 0000-0002-5257-8678
Francesca AmbrogioSection of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0001-5718-7003
Matteo CentonzePersonalized Medicine Laboratory, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Annalisa SchirizziLaboratory of Experimental Oncology, National Institute of Gastroenterology, "IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Giampiero De LeonardisLaboratory of Experimental Oncology, National Institute of Gastroenterology, "IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Rosalba D'AlessandroLaboratory of Experimental Oncology, National Institute of Gastroenterology, "IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0001-9604-366X
Claudio LotesoriereMedical Oncology Unit, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0002-7999-9739
Gianluigi GiannelliScientific Direction, National Institute of Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.

Funding

Italian Ministry of Public Health Ricerca Corrente 2024
6 · The paper itself

Abstract

Autotaxin (ATX) is a member of the ectonucleotide pyrophosphate/phosphodiesterase (

Indexed as

LysophospholipidsNeoplasmsPhosphodiesterase InhibitorsPhosphoric Diester HydrolasesAnimalsCell Transformation, NeoplasticDisease ProgressionDrug Resistance, NeoplasmHumansTumor EscapeLysophospholipidsPhosphodiesterase InhibitorsPhosphoric Diester HydrolasesATX-LPA axisautotaxin (ATX)cancerENPP2lysophosphatidic acid (LPA)lysophosphatidylcholine (LPC)lysophospholipase D (lysoD)tumor microenvironment

Identifiers

PMID39062979
PMCPMC11277072

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.