Evidence map›Paper›PMID 39062944›Full record

ArticleInternational journal of molecular sciences2024

Examination of the Effect of Dimethyl Trisulfide in Acute Stress Mouse Model with the Potential Involvement of the TRPA1 Ion Channel.

Kitti Göntér, Ágnes Dombi, Viktória Kormos, Erika Pintér, Gábor Pozsgai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Age-dependent effects of HFrontiers in psychiatry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kitti GöntérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0009-0006-7022-1724
Ágnes DombiDepartment of Pharmacology, Faculty of Pharmacy, University of Pécs, H-7624 Pécs, Hungary.
Viktória KormosDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-3360-2425
Erika PintérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0001-9898-632X
Gábor PozsgaiDepartment of Pharmacology, Faculty of Pharmacy, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-8524-7162

Funding

Hungarian Academy of Sciences János Bolyai Research Scholarship, BO/00750/22/5National Research, Development and Innovation Office OTKA FK 132454Nemzeti Kutatási, Fejlesztési és Innovaciós Alap ÚNKP-23-5-PTE-1991University of Pecs Research grant of Medical School, KA-2022-29
6 · The paper itself

Abstract

Polysulfides are endogenously produced in mammals and generally associated with protective functions. Our aim was to investigate the effect of dimethyl trisulfide (DMTS) in a mouse model of acute stress. DMTS activates transient receptor potential ankyrin 1 (TRPA1) channels and leads to neuropeptide release, potentially that of substance P (SP). We hypothesize that DMTS might inhibit the degrading enzymes of endocannabinoids, so this system was also investigated as another possible pathway for mediating the effects of DMTS.

Indexed as

Disease Models, AnimalMice, Inbred C57BLMice, KnockoutSulfidesTRPA1 Cation ChannelAnimalsMaleMiceProto-Oncogene Proteins c-fosStress, PhysiologicalStress, PsychologicalSubstance Pdimethyl trisulfideProto-Oncogene Proteins c-fosSubstance PSulfidesTRPA1 Cation ChannelTrpa1 protein, mouseacute stressdimethyl trisulfideendocannabinoidsion channelssubstance PTRPA1

Identifiers

PMID39062944
PMCPMC11277546

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.