Evidence map›Paper›PMID 39062926›Full record

ArticleInternational journal of molecular sciences2024

Deletion of Sphingosine Kinase 2 Attenuates Acute Kidney Injury in Mice with Hemolytic-Uremic Syndrome.

Tina Müller, Nadine Krieg, Antonia I Lange-Polovinkin, Bianka Wissuwa, Markus H Gräler, Sophie Dennhardt, Sina M Coldewey

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tina MüllerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Nadine KriegDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Antonia I Lange-PolovinkinDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Bianka WissuwaDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Markus H GrälerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.ORCID 0000-0001-6650-7849
Sophie DennhardtDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Sina M ColdeweyDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.ORCID 0000-0002-7130-0006

Funding

Federal Ministry of Education and Research 03COV07Federal Ministry of Education and Research 03Z22JN12
6 · The paper itself

Abstract

Typical hemolytic uremic syndrome (HUS) can occur as a severe systemic complication of infections with Shiga toxin (Stx)-producing

Indexed as

Acute Kidney InjuryHemolytic-Uremic SyndromeMice, KnockoutPhosphotransferases (Alcohol Group Acceptor)AnimalsDisease Models, AnimalGene DeletionKidneyMaleMiceMice, Inbred C57BLShiga Toxin 2SphingolipidsSphingosine KinasePhosphotransferases (Alcohol Group Acceptor)Shiga Toxin 2SphingolipidsSphingosine Kinasesphingosine kinase 2, mouseSphk1 protein, mouseceramidescytokineshemolytic-uremic syndromekidney dysfunctionrenal damageShiga toxinsphingolipidssphingosine-1-phosphatesphingosine kinase

Identifiers

PMID39062926
PMCPMC11277509

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.