Evidence map›Paper›PMID 39062897›Full record

ReviewInternational journal of molecular sciences2024

Impact of Respiratory Dust on Health: A Comparison Based on the Toxicity of PM2.5, Silica, and Nanosilica.

Aoxiang Hu, Rou Li, Guo Chen, Shi Chen

Abstract readReviewComparative Study
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aoxiang HuKey Laboratory of Molecular Epidemiology of Hunan Province, Hunan Normal University, Changsha 410013, China.
Rou LiKey Laboratory of Molecular Epidemiology of Hunan Province, Hunan Normal University, Changsha 410013, China.
Guo ChenKey Laboratory of Molecular Epidemiology of Hunan Province, Hunan Normal University, Changsha 410013, China.
Shi ChenKey Laboratory of Molecular Epidemiology of Hunan Province, Hunan Normal University, Changsha 410013, China.ORCID 0000-0002-2961-436X

Funding

National Natural Science Foundation of China 82173493Natural Science Foundation of Hunan Province 2023JJ30423
6 · The paper itself

Abstract

Respiratory dust of different particle sizes in the environment causes diverse health effects when entering the human body and makes acute or chronic damage through multiple systems and organs. However, the precise toxic effects and potential mechanisms induced by dust of different particle sizes have not been systematically summarized. In this study, we described the sources and characteristics of three different particle sizes of dust: PM2.5 (<2.5 μm), silica (<5 μm), and nanosilica (<100 nm). Based on their respective characteristics, we further explored the main toxicity induced by silica, PM2.5, and nanosilica in vivo and in vitro. Furthermore, we evaluated the health implications of respiratory dust on the human body, and especially proposed potential synergistic effects, considering current studies. In summary, this review summarized the health hazards and toxic mechanisms associated with respiratory dust of different particle sizes. It could provide new insights for investigating the synergistic effects of co-exposure to respiratory dust of different particle sizes in mixed environments.

Indexed as

DustNanoparticlesParticle SizeParticulate MatterSilicon DioxideAir PollutantsAnimalsHumansInhalation ExposureAir PollutantsDustParticulate MatterSilicon Dioxidehealth implicationsnanosilicaPM2.5silicatoxicity

Identifiers

PMID39062897
PMCPMC11277548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.