Evidence map›Paper›PMID 39062837›Full record

ArticleInternational journal of molecular sciences2024

Integrating the Idylla™ System Alongside a Real-Time Polymerase Chain Reaction and Next-Generation Sequencing for Investigating Gene Fusions in Pleural Effusions from Non-Small-Cell Lung Cancer Patients: A Pilot Study.

Stefania Scarpino, Alvaro Leone, Dino Galafate, Francesco Pepe, Umberto Malapelle, Sandra Villani, Enrico Giarnieri, Giulio Maurizi, Claudia De Vitis, Rita Mancini and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stefania ScarpinoDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Alvaro LeoneAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.ORCID 0000-0003-3815-9052
Dino GalafateDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Francesco PepeDepartment of Public Health, University of Naples Federico II, 80138 Naples, Italy.ORCID 0000-0002-2803-9586
Umberto MalapelleDepartment of Public Health, University of Naples Federico II, 80138 Naples, Italy.ORCID 0000-0003-3211-9957
Sandra VillaniDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Enrico GiarnieriDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0002-2046-5505
Giulio MauriziDepartment of Thoracic Surgery, Sant' Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Claudia De VitisDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0001-8899-2347
Rita ManciniDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Massimiliano ManciniDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0001-7465-2229
Arianna Di NapoliDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0002-3159-5380
Andrea VecchioneDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0002-5497-6856
Emanuela PilozziDepartment of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0002-7110-9172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant pleural effusion (MPE) from patients with advanced non-small-cell lung cancer (NSCLC) has been proven valuable for molecular analysis; however, simultaneous detection of driver fusions in MPE is still challenging. In this study, we investigated the Idylla™ GeneFusion Panel, a stand-alone test in tissue samples, in the evaluation of

Indexed as

Carcinoma, Non-Small-Cell LungHigh-Throughput Nucleotide SequencingLung NeoplasmsReal-Time Polymerase Chain ReactionAdultAgedAged, 80 and overAnaplastic Lymphoma KinaseFemaleGene FusionHumansMaleMiddle AgedMutationOncogene Proteins, FusionPilot ProjectsAnaplastic Lymphoma KinaseOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-retROS1 protein, humancfRNAgene fusionIdylla™ systemmalignant pleural effusionNSCLC

Identifiers

PMID39062837
PMCPMC11277451

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.