Evidence map›Paper›PMID 39062674›Full record

ArticleGenes2024

Early Non-Invasive Prenatal Testing at 6-9 Weeks of Gestation.

Alexandros Katrachouras, Harry Kontos, Kyriacos Konis, Chara Skentou, George Makrydimas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandros KatrachourasObstetrics and Gynecology, University Hospital of Ioannina, 455 00 Ioannina, Greece.ORCID 0000-0002-4270-0086
Harry KontosDepartment of Molecular Genetics, Genomedica S.A., 185 37 Piraeus, Greece.
Kyriacos KonisObstetrics and Gynecology, General Hospital of Arta, 471 00 Arta, Greece.
Chara SkentouObstetrics and Gynecology, University Hospital of Ioannina, 455 00 Ioannina, Greece.
George MakrydimasObstetrics and Gynecology, University Hospital of Ioannina, 455 00 Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive prenatal testing (NIPT) is usually performed beyond 10 weeks of gestation, because earlier in pregnancy, the fetal fraction is low, resulting in failure to obtain reliable results. This study aimed to evaluate the clinical performance of NIPT earlier in pregnancy using a method for cell-free DNA (cfDNA) analysis that eliminates the need for polymerase chain reaction (PCR), DNA sequencing, or microarrays (Vanadis

Indexed as

Cell-Free Nucleic AcidsGestational AgeNoninvasive Prenatal TestingPregnancy Trimester, FirstAdultFemaleHumansMalePregnancyPrenatal DiagnosisCell-Free Nucleic Acidscell-free DNAfetal screeninglow fetal fractionNIPTVanadis cfDNA test

Identifiers

PMID39062674
PMCPMC11275238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.