Evidence map›Paper›PMID 39062569›Full record

ArticleBiomolecules2024

Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lisosan G.

Silvia Bongiorni, Elisabetta Catalani, Ivan Arisi, Francesca Lazzarini, Simona Del Quondam, Kashi Brunetti, Davide Cervia, Giorgio Prantera

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia BongiorniDepartment of Ecological and Biological Sciences (DEB), University of Tuscia, 01100 Viterbo, Italy.
Elisabetta CatalaniDepartment for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-1210-6836
Ivan ArisiBioinformatics Facility, European Brain Research Institute (EBRI) "Rita Levi-Montalcini", 00161 Rome, Italy.
Francesca LazzariniDepartment of Ecological and Biological Sciences (DEB), University of Tuscia, 01100 Viterbo, Italy.
Simona Del QuondamDepartment for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), University of Tuscia, 01100 Viterbo, Italy.
Kashi BrunettiDepartment for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), University of Tuscia, 01100 Viterbo, Italy.
Davide CerviaDepartment for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-2727-9449
Giorgio PranteraDepartment of Ecological and Biological Sciences (DEB), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0003-0970-9561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) brains are histologically marked by the presence of intracellular and extracellular amyloid deposits, which characterize the onset of the disease pathogenesis. Increasing evidence suggests that certain nutrients exert a direct or indirect effect on amyloid β (Aβ)-peptide production and accumulation and, consequently, on AD pathogenesis. We exploited the fruit fly

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesDisease Models, AnimalDrosophila melanogasterAnimalsAntioxidantsApoptosisAutophagyBiological ProductsBrainPeptide FragmentsReactive Oxygen SpeciesAmyloid beta-Peptidesamyloid beta-protein (1-42)AntioxidantsBiological ProductsPeptide FragmentsReactive Oxygen SpeciesAlzheimer’s diseaseamyloid β peptidesbrain neurodegenerationDrosophila model systemLisosan Gnatural compoundsnutraceuticals

Identifiers

PMID39062569
PMCPMC11274821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.