Evidence map›Paper›PMID 39062542›Full record

ArticleBiomolecules2024

Retinal Vascular and Structural Changes in the Murine Alzheimer's

Lidia Sánchez-Puebla, Inés López-Cuenca, Elena Salobrar-García, María González-Jiménez, Alberto Arias-Vázquez, José A Matamoros, Ana I Ramírez, José A Fernández-Albarral, Lorena Elvira-Hurtado, Takaomi C Saido and 7 more

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Early and progressive retinal microglial changes in APPFrontiers in aging neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lidia Sánchez-PueblaRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-4430-8782
Inés López-CuencaRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0511-515X
Elena Salobrar-GarcíaRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5939-5551
María González-JiménezRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.
Alberto Arias-VázquezRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.
José A MatamorosRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0607-5225
Ana I RamírezRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2656-4723
José A Fernández-AlbarralRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0399-7996
Lorena Elvira-HurtadoRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0300-2602
Takaomi C SaidoLaboratory for Proteolytic Neuroscience, Brain Science Institute, RIKEN, Wako 351-0198, Japan.
Takashi SaitoInstitute of Brain Science, Faculty of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.ORCID 0000-0002-9659-9251
Carmen Nieto-VaqueroCentro Nacional de Investigaciones Cardiovasculares (CNIC), Neurovascular Pathophysiology, Cardiovascular Risk Factor and Brain Function Programme, 28029 Madrid, Spain.
María I CuarteroHospital 12 de Octubre Research Institute (i + 12), 28029 Madrid, Spain.
María A MoroCentro Nacional de Investigaciones Cardiovasculares (CNIC), Neurovascular Pathophysiology, Cardiovascular Risk Factor and Brain Function Programme, 28029 Madrid, Spain.
Juan J SalazarRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5480-5902
Rosa de HozRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1581-087X
José M RamírezRamon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-5145-5094

Funding

Spanish Ministry of Science and Innovation Research Network RETIBRAIN (RED2018-102499-T)universidad complutense de Madrid (CT82/20-CT83/20)Universidad Complutenses de Madrid (CT58/21-CT59/21)
6 · The paper itself

Abstract

Alzheimer's disease (AD) may manifest retinal changes preceding brain pathology. A transversal case-control study utilized spectral-domain OCT angiography (SD-OCTA) and Angio-Tool software 0.6a to assess retinal vascular structures and OCT for inner and outer retina thickness in the

Indexed as

Alzheimer DiseaseDisease Models, AnimalRetinal VesselsTomography, Optical CoherenceAmyloid beta-Protein PrecursorAnimalsCase-Control StudiesFemaleHumansMaleMiceMice, TransgenicRetinaAmyloid beta-Protein PrecursorAlzheimer’s diseaseAPPNL-F/NL-FOCTOCTAretina

Identifiers

PMID39062542
PMCPMC11274728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.