Evidence map›Paper›PMID 39062474›Full record

ReviewBiomolecules2024

Electroceuticals and Magnetoceuticals in Gastroenterology.

Gengqing Song, Roberta Sclocco, Amol Sharma, Ingrid Guerrero-López, Braden Kuo

Abstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Parkinson Disease and the Gut: A Primer for Gastroenterologists.The American journal of gastroenterology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gengqing SongDivision of Gastroenterology & Hepatology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH 44109, USA.ORCID 0000-0001-5551-1818
Roberta ScloccoDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Amol SharmaDivision of Gastroenterology & Hepatology, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-5843-1220
Ingrid Guerrero-LópezFaculty of Medicine, University of Vic-Central University of Catalonia, 08500 Vic, Spain.
Braden KuoDivision of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA.

Funding

Synergistic gut-brain axis modulation via vagal stimulation and cognitive behavioral therapy in functional dyspepsiaR01DK136243 · NIDDK · SPAULDING REHABILITATION HOSPITAL · PI Roberta Sclocco · 2024 to 2026
$2.2M
Body Region Specificity for Neuromodulation of the Gut-Brain Axis in Functional DyspepsiaK01AT012208 · NCCIH · SPAULDING REHABILITATION HOSPITAL · PI Roberta Sclocco · 2023 to 2026
$541k
Non-invasive assessment and modulation of brain-gut interoception in humansR21AT011918 · NCCIH · SPAULDING REHABILITATION HOSPITAL · PI NAPADOW, VITALY, SCLOCCO, ROBERTA · 2023 to 2024
$484k
NCCIH NIH HHS K01 AT012208NCCIH NIH HHS R21 AT011918NIDDK NIH HHS R01 DK136243
6 · The paper itself

Abstract

In the realm of gastroenterology, the inadequacy of current medical treatments for gastrointestinal (GI) motility disorders and inflammatory bowel disease (IBD), coupled with their potential side effects, necessitates novel therapeutic approaches. Neuromodulation, targeting the nervous system's control of GI functions, emerges as a promising alternative. This review explores the promising effects of vagal nerve stimulation (VNS), magnetic neuromodulation, and acupuncture in managing these challenging conditions. VNS offers targeted modulation of GI motility and inflammation, presenting a potential solution for patients not fully relieved from traditional medications. Magnetic neuromodulation, through non-invasive means, aims to enhance neurophysiological processes, showing promise in improving GI function and reducing inflammation. Acupuncture and electroacupuncture, grounded in traditional medicine yet validated by modern science, exert comprehensive effects on GI physiology via neuro-immune-endocrine mechanisms, offering relief from motility and inflammatory symptoms. This review highlights the need for further research to refine these interventions, emphasizing their prospective role in advancing patient-specific management strategies for GI motility disorders and IBD, thus paving the way for a new therapeutic paradigm.

Indexed as

Gastrointestinal MotilityInflammatory Bowel DiseasesAcupuncture TherapyAnimalsElectroacupunctureGastroenterologyGastrointestinal DiseasesHumansVagus Nerve Stimulationacupunctureelectroacupuncturegastrointestinal motility disordersinflammatory bowel diseasemagnetic neuromodulationneuromodulationvagal nerve stimulation

Identifiers

PMID39062474
PMCPMC11275046

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.