ArticleChildren (Basel, Switzerland)2024
Optimizing Newborn Outcomes in Cesarean Sections: A Comparative Analysis of Stress Indicators under General and Spinal Anesthesia.
Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Delivery Routes and Anesthesia Affect Cord Blood NGF, BDNF, and Neonatal Outcomes.Journal of clinical laboratory analysis · 2026Article
- Mode of Anesthesia During Cesarean Section and Neonatal Morbidity and Mortality: A Cohort Study.Local and regional anesthesia · 2026Article
- Salivary Substance P Levels During Cesarean Section Under Spinal versus General Anesthesia: A Prospective Study.Journal of pain research · 2026Article
- The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective.Children (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
BACKGROUND AND
objectivesThe moment of birth represents a complex physiological process that is followed by adaptive changes in the vital systems of the newborn. Such reactions have their positive but also negative effects. The aim of this research was to determine the difference in laboratory values of stress indicators in newborn children delivered by cesarean section (CS) with general and spinal anesthesia. We attempted to make a recommendation about the optimal type of anesthesia based on our results. MATERIALS AND
methodsThe study was performed on 150 healthy term newborns delivered by urgent or planned CS. Samples for adrenocorticotropic hormone (ACTH), cortisol, triglycerides, and interleukin-6 (IL-6) were analyzed.
resultsLeukocyte numbers, triglycerides, and blood sugar values were normal for the newborns' age, with statistically significantly lower values of blood sugar and triglycerides in newborns delivered by CS in spinal anesthesia (
conclusionsIn cases where vaginal delivery is not possible, when CS is indicated, the use of well-controlled spinal anesthesia is followed by lower degrees of metabolic, inflammatory, and stress responses and better vitality of the baby upon birth.
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