Evidence map›Paper›PMID 39062170›Full record

ArticleBiomedicines2024

Diagnoses and Treatment Recommendations-Interrater Reliability of Uroflowmetry in People with Multiple Sclerosis.

Anke K Jaekel, Julia Rieger, Anna-Lena Butscher, Sandra Möhr, Oliver Schindler, Fabian Queissert, Aybike Hofmann, Paul Schmidt, Ruth Kirschner-Hermanns, Stephanie C Knüpfer

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anke K JaekelClinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-7359-4047
Julia RiegerClinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.
Anna-Lena ButscherDepartment of Neuro-Urology, Johanniter Rehabilitation Centre Godeshoehe, 53177 Bonn, Germany.ORCID 0000-0001-5556-4610
Sandra MöhrClinic for Neurorehabilitation and Paraplegiology, REHAB Basel, 4055 Basel, Switzerland.ORCID 0000-0001-8843-0846
Oliver SchindlerClinic for Urology, University Hospital Ulm, 89070 Ulm, Germany.ORCID 0009-0002-3910-9540
Fabian QueissertClinic for Urology, University Hospital Münster, 48149 Münster, Germany.ORCID 0000-0003-2486-2740
Aybike HofmannClinic St. Hedwig, Department of Paediatric Urology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-7974-6694
Paul SchmidtStatistical Consulting for Science and Research, Berlin Statistical Consulting for Science and Research, 13086 Berlin, Germany.ORCID 0000-0002-1676-1774
Ruth Kirschner-HermannsClinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.
Stephanie C KnüpferClinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.

Funding

'Förderverein zur Kontinenzforschung und Kontinenzaufklärung e. V.', Karmeliterhöfe, Karme-literstr, 10, 52064 Aachen, Germany 2023/05Open Access Publication Fund of the University of Bonn
6 · The paper itself

Abstract

backgroundUroflowmetry (UF) is an established procedure in urology and is recommended before further investigations of neurogenic lower urinary tract dysfunction (NLUTD). Some authors even consider using UF instead of urodynamics (UD). Studies on the interrater reliability of UF regarding treatment recommendations are rare, and there are no relevant data on people with multiple sclerosis (PwMS). The aim of this study was to investigate the interrater reliability (IRR) of UF concerning diagnosis and therapy in PwMS prospectively.

methodsUF of 92 PwMS were assessed by 4 raters. The diagnostic criteria were normal findings (NFs), detrusor overactivity (DO), detrusor underactivity (DU), detrusor-sphincter dyssynergia (DSD) and bladder outlet obstruction (BOO). The possible treatment criteria were as follows: no treatment (NO), catheter placement (CAT), alpha-blockers, detrusor-attenuating medication, botulinum toxin (BTX), neuromodulation (NM), and physiotherapy/biofeedback (P/BF). IRR was assessed by kappa (κ).

resultsκ of diagnoses were NFs = 0.22; DO = 0.17; DU = 0.07; DSD = 0.14; and BOO = 0.18. For therapies, the highest κ was BTX = 0.71, NO = 0.38 and CAT = 0.44.

conclusionsThere is a high influence of the individual rater. UD should be subject to the same analysis and a comparison should be made between UD and UF. This may have implications for the value of UF in the neuro-urological management of PwMS, although at present UD remains the gold standard for the diagnostics of NLUTD in PwMS.

Indexed as

bladderbladder disordermultiple sclerosisneurogenic

Identifiers

PMID39062170
PMCPMC11274854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.